Kallikrein-kinin system mediated inflammation in Alzheimer's disease in vivo
The Kallikrein-Kinin System (KKS) has been associated to inflammatory and immunogenic
responses in the peripheral and central nervous system by the activation of two receptors …
responses in the peripheral and central nervous system by the activation of two receptors …
Dynorphin A activates bradykinin receptors to maintain neuropathic pain
J Lai, MC Luo, Q Chen, S Ma, LR Gardell… - Nature …, 2006 - nature.com
Dynorphin A is an endogenous opioid peptide that produces non-opioid receptor-mediated
neural excitation. Here we demonstrate that dynorphin induces calcium influx via voltage …
neural excitation. Here we demonstrate that dynorphin induces calcium influx via voltage …
Kinin B1 Receptor Enhances the Oxidative Stress in a Rat Model of Insulin Resistance: Outcome in Hypertension, Allodynia and Metabolic Complications
JP Dias, S Talbot, J Sénécal, P Carayon, R Couture - PloS one, 2010 - journals.plos.org
Background Kinin B1 receptor (B1R) is induced by the oxidative stress in models of diabetes
mellitus. This study aims at determining whether B1R activation could perpetuate the …
mellitus. This study aims at determining whether B1R activation could perpetuate the …
Early upregulation of kinin B1 receptors in retinal microvessels of the streptozotocin‐diabetic rat
M Abdouh, A Khanjari, N Abdelazziz… - British journal of …, 2003 - Wiley Online Library
Retinal microvessel responses to kinin B1 and B2 receptor agonists and antagonists were
investigated in streptozotocin (STZ)‐diabetic rats and age‐matched controls. In addition …
investigated in streptozotocin (STZ)‐diabetic rats and age‐matched controls. In addition …
Autoradiographic analysis of rat brain kinin B1 and B2 receptors: Normal distribution and alterations induced by epilepsy
B Ongali, MM Campos, G Bregola… - Journal of …, 2003 - Wiley Online Library
Kindling‐induced seizures constitute an experimental model of human temporal lobe
epilepsy that is associated with changes in the expression of several inflammatory proteins …
epilepsy that is associated with changes in the expression of several inflammatory proteins …
Bombesin receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database
J Battey, RV Benya, RT Jensen… - IUPHAR/BPS Guide to …, 2019 - journals.ed.ac.uk
Mammalian bombesin (Bn) receptors comprise 3 subtypes: BB 1, BB 2, BB 3 (nomenclature
recommended by the NC-IUPHAR Subcommittee on bombesin receptors,[109]). BB 1 and …
recommended by the NC-IUPHAR Subcommittee on bombesin receptors,[109]). BB 1 and …
Role of kinin B1 and B2 receptors in a rat model of neuropathic pain
M Petcu, JP Dias, B Ongali, G Thibault… - International …, 2008 - Elsevier
Kinin B1 and B2 receptor (R) gene expression (mRNA) is increased in the sensory system
after peripheral nerve injury. This study measured the densities of B1R and B2R binding …
after peripheral nerve injury. This study measured the densities of B1R and B2R binding …
[引用][C] International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences
LMF Leeb-Lundberg, F Marceau, W Müller-Esterl… - Pharmacological …, 2005 - ASPET
Effects of angiotensin-1 converting enzyme inhibition on oxidative stress and bradykinin receptor expression during doxorubicin-induced cardiomyopathy in rats
To evaluate the mechanisms and the impact of the angiotensin-converting enzyme inhibitor
perindopril (P) in a model of doxorubicin (D)-induced cardiotoxicity, male Wistar rats …
perindopril (P) in a model of doxorubicin (D)-induced cardiotoxicity, male Wistar rats …
Targeting kinin receptors for the treatment of neurological diseases
D Rodi, R Couture, B Ongali… - Current pharmaceutical …, 2005 - ingentaconnect.com
Kinins (bradykinin, kallidin and their active metabolites) are peptide autacoids with
established functions in cardiovascular homeostasis, contraction and relaxation of smooth …
established functions in cardiovascular homeostasis, contraction and relaxation of smooth …