Current approaches and developments in transcript profiling of the human placenta

HEJ Yong, SY Chan - Human reproduction update, 2020 - academic.oup.com
BACKGROUND The placenta is the active interface between mother and foetus, bearing the
molecular marks of rapid development and exposures in utero. The placenta is routinely …

[HTML][HTML] The role of the 3rs for understanding and modeling the human placenta

J Costa, R Mackay, SC de Aguiar Greca… - Journal of Clinical …, 2021 - mdpi.com
Modeling the physiology of the human placenta is still a challenge, despite the great number
of scientific advancements made in the field. Animal models cannot fully replicate the …

[HTML][HTML] Placenta transcriptome profiling in intrauterine growth restriction (IUGR)

M Majewska, A Lipka, L Paukszto… - International journal of …, 2019 - mdpi.com
Intrauterine growth restriction (IUGR) is a serious pathological complication associated with
compromised fetal development during pregnancy. The aim of the study was to broaden …

[HTML][HTML] Integration of transcriptome and proteome profiles in placenta accreta reveals trophoblast over-migration as the underlying pathogenesis

N Li, R Hou, C Liu, T Yang, C Qiao, J Wei - Clinical Proteomics, 2021 - Springer
Background Placenta accreta (PA) is a major cause of maternal morbidity and mortality in
modern obstetrics, few studies have explored the underlying molecular mechanisms …

Melatonin administration during the first half of pregnancy improves the reproductive performance of rabbits: Emphasis on ovarian and placental functions

NM Hashem, AS El-Hawy, MF El-Bassiony, A Saber… - Theriogenology, 2023 - Elsevier
This study was designed to investigate the roles of melatonin administration during different
sensitive windows of the first half of pregnancy in the function and gene expression of the …

[HTML][HTML] Placental expression of microRNAs in infants born small for gestational age

H Östling, R Kruse, G Helenius, M Lodefalk - Placenta, 2019 - Elsevier
Introduction The molecular mechanisms behind poor foetal growth are not fully known. The
aim of this study was to explore global microRNA expression in placentas of infants born …

[HTML][HTML] The Impact of SLC2A8 RNA Interference on Glucose Uptake and the Transcriptome of Human Trophoblast Cells

A Lipka, Ł Paukszto, VC Kennedy, AR Tanner… - Cells, 2024 - mdpi.com
While glucose is the primary fuel for fetal growth, the placenta utilizes the majority of glucose
taken up from the maternal circulation. Of the facilitative glucose transporters in the placenta …

[HTML][HTML] Preliminary RNA-seq analysis of long non-coding RNAs expressed in human term placenta

M Majewska, A Lipka, L Paukszto… - International journal of …, 2018 - mdpi.com
Development of particular structures and proper functioning of the placenta are under the
influence of sophisticated pathways, controlled by the expression of substantial genes that …

[HTML][HTML] Characterization of the placental transcriptome through mid to late gestation in the mare

SC Loux, P Dini, H El-Sheikh Ali, T Kalbfleisch, BA Ball - PloS one, 2019 - journals.plos.org
The placenta is a dynamic organ which undergoes extensive remodeling throughout
pregnancy to support, protect and nourish the developing fetus. Despite the importance of …

Comparative transcriptomic analysis of skeletal muscle tissue during prenatal stages in Tongcheng and Yorkshire pig using RNA-seq

H Liu, Y Xi, G Liu, Y Zhao, J Li, M Lei - Functional & integrative genomics, 2018 - Springer
Myogenesis is accompanied by a number of changes in gene expression in mammals, and
the transcriptional events that underlie these processes have not been yet fully elucidated. In …