A review on mass spectrometry-based quantitative proteomics: Targeted and data independent acquisition

V Vidova, Z Spacil - Analytica chimica acta, 2017 - Elsevier
Mass spectrometry (MS) based proteomics have achieved a near-complete proteome
coverage in humans and in several other organisms, producing a wealth of information …

Advanced cell culture techniques for cancer drug discovery

CJ Lovitt, TB Shelper, VM Avery - Biology, 2014 - mdpi.com
Human cancer cell lines are an integral part of drug discovery practices. However, modeling
the complexity of cancer utilizing these cell lines on standard plastic substrata, does not …

Decoding signalling networks by mass spectrometry-based proteomics

C Choudhary, M Mann - Nature reviews Molecular cell biology, 2010 - nature.com
Signalling networks regulate essentially all of the biology of cells and organisms in normal
and disease states. Signalling is often studied using antibody-based techniques such as …

Strategies for large-scale targeted metabolomics quantification by liquid chromatography-mass spectrometry

J Zhou, Y Yin - Analyst, 2016 - pubs.rsc.org
Advances in liquid chromatography-mass spectrometry (LC-MS) instruments and analytical
strategies have brought about great progress in targeted metabolomics analysis. This …

Mass spectrometry–based proteomics in cell biology

TC Walther, M Mann - Journal of Cell Biology, 2010 - rupress.org
The global analysis of protein composition, modifications, and dynamics are important goals
in cell biology. Mass spectrometry (MS)–based proteomics has matured into an attractive …

A review of the effects of major atmospheric pollutants on pollen grains, pollen content, and allergenicity

H Sénéchal, N Visez, D Charpin… - The Scientific World …, 2015 - Wiley Online Library
This review summarizes the available data related to the effects of air pollution on pollen
grains from different plant species. Several studies carried out either on in situ harvested …

Temporal regulation of EGF signalling networks by the scaffold protein Shc1

Y Zheng, C Zhang, DR Croucher, MA Soliman… - Nature, 2013 - nature.com
Cell-surface receptors frequently use scaffold proteins to recruit cytoplasmic targets, but the
rationale for this is uncertain. Activated receptor tyrosine kinases, for example, engage …

Redox proteomics: chemical principles, methodological approaches and biological/biomedical promises

A Bachi, I Dalle-Donne, A Scaloni - Chemical reviews, 2013 - ACS Publications
Inevitable byproducts of aerobic metabolism are free radicals and other highly reactive
oxidants and nitrosants that are continuously formed within cells. Most cells generally …

In vitro reconstitution of mevalonate pathway and targeted engineering of farnesene overproduction in Escherichia coli

F Zhu, X Zhong, M Hu, L Lu, Z Deng… - Biotechnology and …, 2014 - Wiley Online Library
Approaches using metabolic engineering and synthetic biology to overproduce terpenoids,
such as the precursors of taxol and artemisinin, in microbial systems have achieved initial …

Advancing the sensitivity of selected reaction monitoring‐based targeted quantitative proteomics

T Shi, D Su, T Liu, K Tang, DG Camp, WJ Qian… - …, 2012 - Wiley Online Library
Selected reaction monitoring (SRM)–also known as multiple reaction monitoring (MRM)–has
emerged as a promising high‐throughput targeted protein quantification technology for …