Serum 25-hydroxyvitamin D and cancer risk: a systematic review of Mendelian randomization studies
T Lawler, S Warren Andersen - Nutrients, 2023 - mdpi.com
Epidemiological studies suggest that higher serum 25-hydroxyvitamin D is associated with
lower risk for several cancers, including breast, prostate, colorectal, and lung cancers. To …
lower risk for several cancers, including breast, prostate, colorectal, and lung cancers. To …
Systematic review of Mendelian randomization studies on risk of cancer
G Markozannes, A Kanellopoulou, O Dimopoulou… - BMC medicine, 2022 - Springer
Background We aimed to map and describe the current state of Mendelian randomization
(MR) literature on cancer risk and to identify associations supported by robust evidence …
(MR) literature on cancer risk and to identify associations supported by robust evidence …
Bias correction for inverse variance weighting Mendelian randomization
Inverse‐variance weighted two‐sample Mendelian randomization (IVW‐MR) is the most
widely used approach that utilizes genome‐wide association studies (GWAS) summary …
widely used approach that utilizes genome‐wide association studies (GWAS) summary …
Metabolic syndrome, metabolic comorbid conditions and risk of early-onset colorectal cancer
Objective Factors that lead to metabolic dysregulation are associated with increased risk of
early-onset colorectal cancer (CRC diagnosed under age 50). However, the association …
early-onset colorectal cancer (CRC diagnosed under age 50). However, the association …
Genetically proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers: A mendelian randomization analysis
Background Epidemiological studies have reported conflicting findings on the potential
adverse effects of long-term antihypertensive medication use on cancer risk. Naturally …
adverse effects of long-term antihypertensive medication use on cancer risk. Naturally …
Body size and composition and risk of site-specific cancers in the UK Biobank and large international consortia: A mendelian randomisation study
M Vithayathil, P Carter, S Kar, AM Mason… - PLoS …, 2021 - journals.plos.org
Background Evidence for the impact of body size and composition on cancer risk is limited.
This mendelian randomisation (MR) study investigates evidence supporting causal …
This mendelian randomisation (MR) study investigates evidence supporting causal …
Vitamin D and human health: evidence from Mendelian randomization studies
A Fang, Y Zhao, P Yang, X Zhang… - European Journal of …, 2024 - Springer
We summarized the current evidence on vitamin D and major health outcomes from
Mendelian randomization (MR) studies. PubMed and Embase were searched for original …
Mendelian randomization (MR) studies. PubMed and Embase were searched for original …
[HTML][HTML] Coffee consumption and cancer risk: a Mendelian randomisation study
Background Coffee contains many bioactive chemicals and associations with cancer have
been reported in observational studies. In this Mendelian randomisation (MR) study we …
been reported in observational studies. In this Mendelian randomisation (MR) study we …
Lipoproteins and cancer: The role of HDL-C, LDL-C, and cholesterol-lowering drugs
KK Patel, K Kashfi - Biochemical pharmacology, 2022 - Elsevier
Cholesterol is an amphipathic sterol molecule that is vital for maintaining normal
physiological homeostasis. It is a relatively complicated molecule with 27 carbons whose …
physiological homeostasis. It is a relatively complicated molecule with 27 carbons whose …
Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation
Background: Some individuals living with obesity may be relatively metabolically healthy,
whilst others suffer from multiple conditions that may be linked to adverse metabolic effects …
whilst others suffer from multiple conditions that may be linked to adverse metabolic effects …