Mechanisms and Management of Retinopathy of Prematurity | New England Journal of Medicine
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The understanding, diagnosis, and treatment of retinopathy of prematurity have changed in
the 70 years since the original description of retrolental fibroplasia associated with high …

Background: We have previously shown an increased incidence of intermittent hypoxemia
(IH) events in preterm infants with severe retinopathy of prematurity (ROP). Animal models …

In 1942, when retinopathy of prematurity (ROP) first manifested as retrolental fibroplasia, the
technology to monitor or regulate oxygen did not exist, and a fundus examination of preterm …

Objective To explore whether early or late and presumed or definite neonatal bacteremia
are associated with an increased risk of severe retinopathy of prematurity (ROP). Methods …

The role of chorioamnionitis (CA) in the development of retinopathy of prematurity (ROP) is
difficult to establish, because CA-exposed and CA-unexposed infants frequently present …

Retinopathy of prematurity (ROP) continues to be a major preventable cause of blindness
and visual handicaps globally. With improved perinatal care, improved survival of …

Background Mammalian mucosal barriers secrete antimicrobial peptides (AMPs) as critical,
host-derived regulators of the microbiota. However, mechanisms that support microbiota …

Purpose.: To test the hypothesis that the presence of bacteria and/or histologic inflammation
in the placenta of infants born preterm is associated with an increased risk for severe …

Introduction Retinopathy of prematurity (ROP) is a vasoproliferative disorder of the
premature retina with the potential to progress to extraretinal neovascularisation. This review …