Visualizing and manipulating the behavior of proteins is crucial to understanding the
physiology of the cell. Methods of biorthogonal protein labeling are important tools to attain …

Much effort has been put into the optimization of the functional activity of proteins. For
biosensors this protein functional optimization will increase the biosensor's sensitivity and/or …

An 11-residue peptide with the sequence DS LEFIASKLA was identified from a genomic
library of Bacillus subtilis by phage display as an efficient substrate for Sfp …

The ability to specifically attach chemical probes to individual proteins represents a powerful
approach to the study and manipulation of protein function in living cells. It provides a …

Förster resonance energy transfer (FRET) is applied extensively in all fields of biological
research and technology, generally as a 'nanoruler'with a dynamic range corresponding to …

O 6-Alkylguanine-DNA alkyltransferase (AGT) is a widely distributed, unique DNA repair
protein that acts as a single agent to directly remove alkyl groups located on the O 6-position …

Methods to visualize, track, measure and perturb proteins in living cells are central to
biomedicine's efforts to characterize and understand the spatial and temporal underpinnings …

The specific reaction of O 6-alkylguanine-DNA alkyltransferase (AGT) with O 6-
benzylguanine (BG) derivatives allows for a specific labeling of AGT fusion proteins with …

Immobilization of proteins onto surfaces is of great importance in numerous applications,
including protein analysis, drug screening, and medical diagnostics, among others. The …

Glycans are the most abundant biopolymers on earth and are constituents of glycoproteins,
glycolipids, and proteoglycans with multiple biological functions. The availability of different …