Polyunsaturated fatty acids and fatty acid-derived lipid mediators: Recent advances in the understanding of their biosynthesis, structures, and functions
Polyunsaturated fatty acids (PUFAs) are structural components of membrane phospholipids,
and influence cellular function via effects on membrane properties, and also by acting as a …
and influence cellular function via effects on membrane properties, and also by acting as a …
Inflammation and tumor progression: signaling pathways and targeted intervention
H Zhao, L Wu, G Yan, Y Chen, M Zhou… - Signal transduction and …, 2021 - nature.com
Cancer development and its response to therapy are regulated by inflammation, which
either promotes or suppresses tumor progression, potentially displaying opposing effects on …
either promotes or suppresses tumor progression, potentially displaying opposing effects on …
Functions of ROS in macrophages and antimicrobial immunity
M Herb, M Schramm - Antioxidants, 2021 - mdpi.com
Reactive oxygen species (ROS) are a chemically defined group of reactive molecules
derived from molecular oxygen. ROS are involved in a plethora of processes in cells in all …
derived from molecular oxygen. ROS are involved in a plethora of processes in cells in all …
Specialized pro-resolving mediator network: an update on production and actions
Today, persistent and uncontrolled inflammation is appreciated to play a pivotal role in many
diseases, such as cardiovascular diseases, neurodegenerative diseases, metabolic …
diseases, such as cardiovascular diseases, neurodegenerative diseases, metabolic …
Pain-resolving immune mechanisms in neuropathic pain
Interactions between the immune and nervous systems are of central importance in
neuropathic pain, a common and debilitating form of chronic pain caused by a lesion or …
neuropathic pain, a common and debilitating form of chronic pain caused by a lesion or …
Resolvins in inflammation: emergence of the pro-resolving superfamily of mediators
CN Serhan, BD Levy - The Journal of clinical investigation, 2018 - Am Soc Clin Investig
Countless times each day, the acute inflammatory response protects us from invading
microbes, injuries, and insults from within, as in surgery-induced tissue injury. These …
microbes, injuries, and insults from within, as in surgery-induced tissue injury. These …
[HTML][HTML] Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies
The health effects of omega-3 fatty acids have been controversial. Here we report the results
of a de novo pooled analysis conducted with data from 17 prospective cohort studies …
of a de novo pooled analysis conducted with data from 17 prospective cohort studies …
The role of micronutrients in support of the immune response against viral infections
F Pecora, F Persico, A Argentiero, C Neglia, S Esposito - Nutrients, 2020 - mdpi.com
Viral infections are a leading cause of morbidity and mortality worldwide, and the importance
of public health practices including handwashing and vaccinations in reducing their spread …
of public health practices including handwashing and vaccinations in reducing their spread …
[HTML][HTML] The crucial roles of inflammatory mediators in inflammation: A review
The inflammatory response is a crucial aspect of the tissues' responses to deleterious
inflammogens. This complex response involves leukocytes cells such as macrophages …
inflammogens. This complex response involves leukocytes cells such as macrophages …
Immune cell regulation of glia during CNS injury and disease
Glial cells are abundant in the CNS and are essential for brain development and
homeostasis. These cells also regulate tissue recovery after injury and their dysfunction is a …
homeostasis. These cells also regulate tissue recovery after injury and their dysfunction is a …