Detrimental effects of lipid peroxidation in type 2 diabetes: Exploring the neutralizing influence of antioxidants

SC Shabalala, R Johnson, AK Basson, K Ziqubu… - Antioxidants, 2022 - mdpi.com
Lipid peroxidation, including its prominent byproducts such as malondialdehyde (MDA) and
4-hydroxy-2-nonenal (4-HNE), has long been linked with worsened metabolic health in …

Lipidomics in understanding pathophysiology and pharmacologic effects in inflammatory diseases: considerations for drug development

K Ahluwalia, B Ebright, K Chow, P Dave, A Mead… - Metabolites, 2022 - mdpi.com
The lipidome has a broad range of biological and signaling functions, including serving as a
structural scaffold for membranes and initiating and resolving inflammation. To investigate …

On Males, Antioxidants and Infertility (MOXI): Certitudes, Uncertainties and Trends

M Alfaro Gómez, MR Fernández-Santos… - Antioxidants, 2023 - mdpi.com
Male infertility (MI) involves various endogenous and exogenous facts. These include
oxidative stress (OS), which is known to alter several physiological pathways and it is …

Simultaneous determination of DL-cysteine, DL-homocysteine, and glutathione in saliva and urine by UHPLC-Q-Orbitrap HRMS: Application to studies of oxidative …

Q Ma, C Qi, XL Li, Q Shi, CY Xu, T Jin, JZ Min - Journal of Pharmaceutical …, 2021 - Elsevier
A high-sensitivity and-selectivity mass spectrometry derivatization reagent,(R)-(5-(3-
isothiocyanatopyrrolidin-1-yl)-5-oxopentyl) triphenylphosphonium (NCS-OTPP), was …

Modeling and optimization of malondialdehyde (MDA) absorbance behavior through response surface methodology (RSM) and artificial intelligence network (AIN): An …

B Akbari, F Najafi, M Bahmaei… - Journal of …, 2023 - Wiley Online Library
Oxidative stress (OS) associated with reactive oxygen species (ROS) attacks many
biomolecules, leading to cell death, lipid peroxidation (LP), and physiological mechanism …

Ambient exposure to fine particulate matter with oxidative potential affects oxidative stress biomarkers in pregnancy

Q Meng, J Liu, J Shen, I Del Rosario… - American Journal of …, 2025 - academic.oup.com
Prenatal exposures to ambient particulate matter (PM2. 5) from traffic may generate
oxidative stress and thus contribute to adverse birth outcomes. We investigated whether …

LC-MS/MS based analytical strategies for the detection of lipid peroxidation products in biological matrices

F Fanti, M Sergi, D Compagnone - Journal of Pharmaceutical and …, 2025 - Elsevier
Oxidative stress (OS) arises mainly from exposure to reactive oxygen species (ROS) such as
superoxide anion, hydroxyl radical, and hydrogen peroxide. These molecules can cause …

[HTML][HTML] Rapid and reliable quantification of urinary malondialdehyde by HILIC-MS/MS: A derivatization-free breakthrough approach

G Chango, D García-Gómez, CG Pinto… - Analytica Chimica …, 2024 - Elsevier
Background The development of fast analytical methods is crucial for the research,
discovery, and confirmation of crucial biomarkers. Furthermore, the implementation of fast …

Comparison of colorimetric methods to detect malondialdehyde, A biomarker of reactive oxygen species

D Islayem, FB Fakih, S Lee - ChemistrySelect, 2022 - Wiley Online Library
Excessive production of reactive oxygen species (ROS) is implicated in the pathogenesis of
aging‐related disorders such as cardiovascular diseases. However, monitoring of ROS in …

Malondialdehyde Analysis in Biological Samples by Capillary Electrophoresis: The State of Art

MP do Nascimento, B Marchiori Berlande… - Critical Reviews in …, 2023 - Taylor & Francis
Lipid peroxidation occurs when substances, such as reactive oxygen species, attack lipids.
Polyunsaturated fatty acids are the main targets. Several products are formed, including …