Latest developments in coumarin-based anticancer agents: mechanism of action and structure–activity relationship studies
Many researchers around the world are working on the development of novel anticancer
drugs with different mechanisms of action. In this case, coumarin is a highly promising …
drugs with different mechanisms of action. In this case, coumarin is a highly promising …
Coumarin-containing hybrids and their anticancer activities
L Zhang, Z Xu - European Journal of Medicinal Chemistry, 2019 - Elsevier
Cancer is the second leading cause of death worldwide, and it results in around 9 million
deaths annually. The anticancer agents play an intriguing role in the treatment of cancers …
deaths annually. The anticancer agents play an intriguing role in the treatment of cancers …
Investigations on some coumarin based corrosion inhibitors for mild steel in aqueous acidic medium: Electrochemical, surface morphological, density functional theory …
Abstract Two coumarin derivatives, namely, 3-(3-benzyl-4-hydroxy-2-thioxo-3, 4-dihydro-2H-
1, 3-thiazin-6-yl)-8-methoxy-2H-chromen-2-one (BTMC) and 3-(3-benzyl-4-hydroxy-2 thioxo …
1, 3-thiazin-6-yl)-8-methoxy-2H-chromen-2-one (BTMC) and 3-(3-benzyl-4-hydroxy-2 thioxo …
Coumarin-benzothiazole based azo dyes: synthesis, characterization, computational, photophysical and biological studies
B Manjunatha, YD Bodke, O Nagaraja… - Journal of Molecular …, 2021 - Elsevier
In this paper, we have reported the synthesis of some coumarin-benzothiazole based azo
dyes (C 1-C 5). The structure of the synthesised dyes was precisely established from their …
dyes (C 1-C 5). The structure of the synthesised dyes was precisely established from their …
E-pharmacophore modelling, virtual screening, molecular dynamics simulations and in-silico ADME analysis for identification of potential E6 inhibitors against cervical …
DNA of high-risk HPV 16 and 18 has been found to be associated with nearly 90% cases of
cervical cancer. The viral E6 and E7 genes of HPV are regularly maintained and expressed …
cervical cancer. The viral E6 and E7 genes of HPV are regularly maintained and expressed …
Structural variety of Cu (II), Ni (II), and Co (II) complexes of a hydrazone based on 5‐acetyl‐4‐hydroxy‐2H‐1, 3‐thiazine‐2, 6 (3H)‐dione: Synthesis, spectroscopic …
New nickel (II), cobalt (II), and several copper (II) complexes have been synthesized from the
hydrazone ligand (AHTDSH; H2L); which obtained from 5‐acetyl‐4‐hydroxy‐2H‐1, 3 …
hydrazone ligand (AHTDSH; H2L); which obtained from 5‐acetyl‐4‐hydroxy‐2H‐1, 3 …
Synthesis, spectroscopic studies, DFT calculations, antimicrobial and antitumor activity of tridentate NNO Schiff base metal complexes based on 5-acetyl-4-hydroxy-2H …
New Schiff base ligand was prepared by condensation of 5-acetyl-4-hydroxy-2H-1, 3-
thiazine-2, 6 (3H)-dione with o-phenylenediamine. Cu (II), Ni (II), Co (II), VO (IV), Zn (II), Cd …
thiazine-2, 6 (3H)-dione with o-phenylenediamine. Cu (II), Ni (II), Co (II), VO (IV), Zn (II), Cd …
Selective Metal‐Coordinated Nanodrugs Based on Thiazine Moiety for Anticancer Therapeutics: Spectroscopic, Theoretical, and Molecular Docking Studies
The current study involved production, comprehensive structural analysis, and
physicochemical characterizing of two distinctive complexes namely, Cu (TBH) and Zn …
physicochemical characterizing of two distinctive complexes namely, Cu (TBH) and Zn …
Multicomponent synthetic strategies and perspectives for synthesis of linked or fused coumarin heterocycles
S Pasricha, K Mittal, P Gahlot, H Kaur, N Avasthi… - Journal of the Iranian …, 2022 - Springer
Natural and synthetic hybrid molecules are an attractive scaffold for therapeutic agent
development due to their dual/multiple modes of action, minimum or no side effects …
development due to their dual/multiple modes of action, minimum or no side effects …
Synthesis, antitubercular evaluation, molecular docking and molecular dynamics studies of 4, 6-disubstituted-2-oxo-dihydropyridine-3-carbonitriles
A new series of novel diphenyl ether based 2-oxo-dihydropyridine derivatives were
synthesized and screened for their in vitro antimycobacterial and antibacterial activities …
synthesized and screened for their in vitro antimycobacterial and antibacterial activities …