The role of microenvironment in tumor angiogenesis

X Jiang, J Wang, X Deng, F Xiong, S Zhang… - Journal of Experimental …, 2020 - Springer
Tumor angiogenesis is necessary for the continued survival and development of tumor cells,
and plays an important role in their growth, invasion, and metastasis. The tumor …

Current advances in RNA therapeutics for human diseases

H Zogg, R Singh, S Ro - International journal of molecular sciences, 2022 - mdpi.com
Following the discovery of nucleic acids by Friedrich Miescher in 1868, DNA and RNA were
recognized as the genetic code containing the necessary information for proper cell …

The non-canonical aspects of microRNAs: many roads to gene regulation

CJ Stavast, SJ Erkeland - Cells, 2019 - mdpi.com
MicroRNAs (miRNAs) are critical regulators of gene expression. As miRNAs are frequently
deregulated in many human diseases, including cancer and immunological disorders, it is …

MicroRNA in control of gene expression: an overview of nuclear functions

C Catalanotto, C Cogoni, G Zardo - International journal of molecular …, 2016 - mdpi.com
The finding that small non-coding RNAs (ncRNAs) are able to control gene expression in a
sequence specific manner has had a massive impact on biology. Recent improvements in …

Role of the tumor microenvironment in PD-L1/PD-1-mediated tumor immune escape

X Jiang, J Wang, X Deng, F Xiong, J Ge, B Xiang, X Wu… - Molecular cancer, 2019 - Springer
Tumor immune escape is an important strategy of tumor survival. There are many
mechanisms of tumor immune escape, including immunosuppression, which has become a …

Towards a molecular understanding of microRNA-mediated gene silencing

S Jonas, E Izaurralde - Nature reviews genetics, 2015 - nature.com
MicroRNAs (miRNAs) are a conserved class of small non-coding RNAs that assemble with
Argonaute proteins into miRNA-induced silencing complexes (miRISCs) to direct post …

An overview of microRNAs

SM Hammond - Advanced drug delivery reviews, 2015 - Elsevier
The discovery of the first microRNA (miRNA) over 20 years ago has ushered in a new era in
molecular biology. There are now over 2000 miRNAs that have been discovered in humans …

The functions of microRNAs: mRNA decay and translational repression

H Iwakawa, Y Tomari - Trends in cell biology, 2015 - cell.com
MicroRNAs (miRNAs) are a class of endogenous small noncoding RNAs, which regulate
complementary mRNAs by inducing translational repression and mRNA decay. Although …

Toxicity of graphene-family nanoparticles: a general review of the origins and mechanisms

L Ou, B Song, H Liang, J Liu, X Feng, B Deng… - Particle and fibre …, 2016 - Springer
Due to their unique physicochemical properties, graphene-family nanomaterials (GFNs) are
widely used in many fields, especially in biomedical applications. Currently, many studies …

[HTML][HTML] The noncoding RNA revolution—trashing old rules to forge new ones

TR Cech, JA Steitz - Cell, 2014 - cell.com
Noncoding RNAs (ncRNAs) accomplish a remarkable variety of biological functions. They
regulate gene expression at the levels of transcription, RNA processing, and translation …