To better understand the reward circuitry in human brain, we conducted activation likelihood
estimation (ALE) and parametric voxel-based meta-analyses (PVM) on 142 neuroimaging …

Reward maximization is a core motivation of every organism. In humans, several brain
regions have been implicated in the representation of reward magnitude. Still, it is unclear …

Understanding how the brain computes value is a basic question in neuroscience. Although
individual studies have driven this progress, meta-analyses provide an opportunity to test …

Louann Brizendine, MD, is a neuropsychiatrist whose professional career has been devoted
to studying the female brain and writing and lecturing to both the public and professionals …

Recent models hypothesize that adolescents' risky behavior is the consequence of
increased sensitivity to rewards in the ventral medial (VM) prefrontal cortex (PFC) and the …

In our everyday life, we often have to make decisions with risky consequences, such as
choosing a restaurant for dinner or choosing a form of retirement saving. To date, however …

Economists define risk in terms of the variability of possible outcomes, whereas clinicians
and laypeople generally view risk as exposure to possible loss or harm. Neuroeconomic …

It has been shown that in certain situations losses exert a stronger effect on behavior than
respective gains, and this has been commonly explained by the argument that losses are …

Abstract The Iowa Gambling Task (IGT) is a sensitive test for the detection of decision‐
making impairments in several neurological and psychiatric populations. Very few studies …

Recent evidence suggests considerable overlap between the default mode network (DMN)
and regions involved in social, affective and introspective processes. We considered these …