Preeclampsia Preeclampsia complicates 2 to 4% of all pregnancies and accounts for about
46,000 maternal deaths and 500,000 fetal or newborn deaths each year. Antihypertensive …

Pre-eclampsia is a multisystem pregnancy disorder characterised by variable degrees of
placental malperfusion, with release of soluble factors into the circulation. These factors …

Preeclampsia is pregnancy-specific, and significantly contributes to maternal, and perinatal
morbidity and mortality worldwide. An effective predictive test for preeclampsia would …

Two important maternal cardiometabolic disorders (CMDs), hypertensive disorders in
pregnancy (HDP)(including pre-eclampsia) and gestational diabetes mellitus (GDM), result …

Objective To evaluate whether extended release metformin could be used to prolong
gestation in women being expectantly managed for preterm pre-eclampsia. Design …

Background Preeclampsia remains a major cause of maternal and neonatal morbidity and
mortality. Biologic plausibility, compelling preliminary data, and a pilot clinical trial support …

The importance of a fully functioning placenta for a good pregnancy outcome is
unquestioned. Loss of function can lead to pregnancy complications and is often detected by …

Despite intensive investigation, we still cannot adequately predict, treat, or prevent
preeclampsia. We have gained awareness that preeclampsia is a syndrome not a disease …

Preeclampsia (PE) is a leading cause of maternal and neonatal mortality and morbidity
worldwide, impacting the long‐term health of both mother and offspring. PE has long been …

Prevention of preeclampsia (PE) remains one of the most significant problems in perinatal
medicine. Due to the possible unpredictable course of hypertension in pregnancy, primarily …