Mitochondria exist as dynamic networks that often change shape and subcellular
distribution. The number and morphology of mitochondria within a cell are controlled by …

Mitochondria form dynamic tubular networks that continually change their shape and move
throughout the cell. In eukaryotes, these organellar gymnastics are controlled by numerous …

Abstract The dynamin-related GTPase Dnm1 controls mitochondrial morphology in yeast.
Here we show that dnm1 mutations convert the mitochondrial compartment into a planar …

Mitochondrial division is important for mitochondrial distribution and function. Recent data
have demonstrated that ER–mitochondria contacts mark mitochondrial division sites, but the …

Mitochondria are double-membrane enclosed eukaryotic organelles with a central role in
numerous cellular functions. The ultrastructure of mitochondria varies considerably between …

Disruption of axonal transport leads to a disorganized distribution of mitochondria and other
organelles and is thought to be responsible for some types of neuronal disease. The reason …

Mitochondrial DNA (mtDNA) encodes essential components of the cellular energy-
producing apparatus, and lesions in mtDNA and mitochondrial dysfunction contribute to …

The understanding of the processes underlying organellar function and inheritance requires
the identification and characterization of the molecular components involved. We pursued a …

The actin cytoskeleton provides the structural basis for cell polarity in Saccharomyces
cerevisiae as well as most other eukaryotes. In Part I of this two-part commentary, presented …

The Saccharomyces cerevisiae Dnm1 protein is structurally related to dynamin, a GTPase
required for membrane scission during endocytosis. Here we show that Dnm1p is essential …