Although the complement system is primarily perceived as a host defence system, a more
versatile, yet potentially more harmful side of this innate immune pathway as an …

Glial cell types were classified less than 100 years ago by del Rio-Hortega. For instance, he
correctly surmised that microglia in pathologic central nervous system (CNS) were …

Importance The ability to predict neurodevelopmental impairment (NDI) for infants
diagnosed with hypoxic ischemic encephalopathy (HIE) is important for parental guidance …

Astrocytes maintain the homeostasis of the central nervous system (CNS) by eg recycling of
neurotransmitters and providing nutrients to neurons. Astrocytes function also as key …

The complement system plays critical roles in development, homeostasis, and regeneration
in the central nervous system (CNS) throughout life; however, complement dysregulation in …

Stroke is an acute insult to the central nervous system (CNS) that triggers a sequence of
responses in the acute, subacute as well as later stages, with prominent involvement of …

Spinal cord injury (SCI) has a complex pathophysiology. Following the initial physical
trauma to the spinal cord, which may cause vascular disruption, hemorrhage, mechanical …

The complement cascade is a key component of the innate immune system that is rapidly
recruited through a cascade of enzymatic reactions to enable the recognition and clearance …

Astrocytes, which are homeostatic cells of the central nervous system (CNS), display
remarkable heterogeneity in their morphology and function. Besides their physical and …

The complement cascade is an important arm of the immune system that plays a key role in
protecting the central nervous system (CNS) from infection. Recently, it has also become …