[HTML][HTML] Drug-induced oxidative stress in cancer treatments: Angel or devil?

H Jiang, J Zuo, B Li, R Chen, K Luo, X Xiang, S Lu… - Redox Biology, 2023 - Elsevier
Oxidative stress (OS), defined as redox imbalance in favor of oxidant burden, is one of the
most significant biological events in cancer progression. Cancer cells generally represent a …

[HTML][HTML] The antioxidant potential of different edible and medicinal mushrooms

RW Mwangi, JM Macharia, IN Wagara… - Biomedicine & …, 2022 - Elsevier
Mushroom consumption has grown extraordinarily owing to their high nutritional value,
desirable taste, and aroma. Mushrooms continue generating lots of interest chiefly in their …

Molecular changes induced by oxidative stress that impair human sperm motility

K Nowicka-Bauer, B Nixon - Antioxidants, 2020 - mdpi.com
A state of oxidative stress (OS) and the presence of reactive oxygen species (ROS) in the
male reproductive tract are strongly correlated with infertility. While physiological levels of …

The NRF2, thioredoxin, and glutathione system in tumorigenesis and anticancer therapies

M Jaganjac, L Milkovic, SB Sunjic, N Zarkovic - Antioxidants, 2020 - mdpi.com
Cancer remains an elusive, highly complex disease and a global burden. Constant change
by acquired mutations and metabolic reprogramming contribute to the high inter-and …

[HTML][HTML] Intestinal permeability in the pathogenesis of liver damage: From non-alcoholic fatty liver disease to liver transplantation

A Nicoletti, FR Ponziani, M Biolato… - World journal of …, 2019 - ncbi.nlm.nih.gov
The intimate connection and the strict mutual cooperation between the gut and the liver
realizes a functional entity called gut-liver axis. The integrity of intestinal barrier is crucial for …

Dysregulation of Nrf2 in hepatocellular carcinoma: role in cancer progression and chemoresistance

A Raghunath, K Sundarraj, F Arfuso, G Sethi… - Cancers, 2018 - mdpi.com
The liver executes versatile functions and is the chief organ for metabolism of
toxicants/xenobiotics. Hepatocellular carcinoma (HCC) is the most common primary liver …

MicroRNA networks modulate oxidative stress in cancer

YH Lin - International journal of molecular sciences, 2019 - mdpi.com
Imbalanced regulation of reactive oxygen species (ROS) and antioxidant factors in cells is
known as “oxidative stress (OS)”. OS regulates key cellular physiological responses through …

[HTML][HTML] Molecular mechanisms of ROS-modulated cancer chemoresistance and therapeutic strategies

X Zhou, B An, Y Lin, Y Ni, X Zhao, X Liang - Biomedicine & …, 2023 - Elsevier
Drug resistance is the main obstacle to achieving a cure in many cancer patients. Reactive
oxygen species (ROS) are master regulators of cancer development that act through …

Control of oxidative stress in cancer chemoresistance: spotlight on Nrf2 role

G Barrera, MA Cucci, M Grattarola, C Dianzani… - Antioxidants, 2021 - mdpi.com
Chemoresistance represents the main obstacle to cancer treatment with both conventional
and targeted therapy. Beyond specific molecular alterations, which can lead to targeted …

[HTML][HTML] Oxidative stress and redox signaling in the pathophysiology of liver diseases

RGR Mooli, D Mukhi… - Comprehensive …, 2022 - ncbi.nlm.nih.gov
The increased production of derivatives of molecular oxygen and nitrogen in the form of
reactive oxygen species (ROS) and reactive nitrogen species (RNS) lead to molecular …