Autism spectrum disorder (ASD) is a highly heterogeneous neurodevelopmental disorder
characterized by communication and social behavior deficits. The presence of restricted and …

The question of how same-gene mutations can drive both cancer and neurodevelopmental
disorders has been puzzling. It has also been puzzling why those with neurodevelopmental …

Synaptic potentiation underlies various forms of behavior and depends on modulation by
multiple activity-dependent transcription factors to coordinate the expression of genes …

Abstract Intellectual and Developmental Disabilities (IDDs), such as Down syndrome,
Fragile X syndrome, Rett syndrome, and autism spectrum disorder, usually manifest at birth …

Introduction Heart failure (HF) is a heterogeneous clinical syndrome and affects millions of
people all over the world. HF occurs when the cardiac overload and injury, which is a …

Abstract Coronavirus disease 2019 (COVID-19) is an infectious disease caused by the
newly discovered coronavirus, SARS-CoV-2. Increased severity of COVID-19 has been …

Stroke is the second largest cause of mortality in the world. Genome-wide association
studies (GWAS) have identified some genetic variants associated with stroke risk, but their …

Accounting for cell type compositions has been very successful at analyzing high-throughput
data from heterogeneous tissues. Differential gene expression analysis at cell type level is …

Although the identification of numerous genes involved in neurodevelopmental disorders
(NDDs) has reshaped our understanding of their etiology, there are still major obstacles in …

Autism spectrum disorder (ASD) is one of the common neurodevelopmental disorders in
children. Its etiology and pathogenesis are poorly understood. Previous studies have …