Strains of Clostridioides difficile cause detrimental diarrheas with thousands of deaths
worldwide. The infection process by the Gram-positive, strictly anaerobic gut bacterium is …

Antimicrobial resistance to treatments for Clostridioides difficile infection (CDI) poses a
significant threat to global health. C. difficile is widely thought to be susceptible to oral …

Clostridioides difficile is a pathogenic bacterium that infects the human colon to cause
diarrheal disease. Growth of the bacterium is known to be dependent on certain bile acids …

Clostridium difficile is the leading cause of hospital-acquired antibiotic-associated diarrhea
and is the only widespread human pathogen that contains a complete set of genes encoding …

Antibiotics alter the gut microbiota and decrease resistance to Clostridium difficile
colonization; however, the mechanisms driving colonization resistance are not well …

The obligate anaerobe, spore forming bacterium Clostridioides difficile (formerly Clostridium
difficile) causes nosocomial and community acquired diarrhea often associated with …

The emerging human enteropathogen Clostridioides difficile is the main cause of diarrhea
associated with antibiotherapy. Regulatory pathways underlying the adaptive responses …

The response to iron limitation of several bacteria is regulated by the ferric uptake regulator
(Fur). The Fur-regulated transcriptional, translational and metabolic networks of the Gram …

Objectives The identification and characterization of clinical Clostridioides difficile isolates
with reduced fidaxomicin susceptibility. Methods Agar dilution assays were used to …

The anaerobic pathogen Clostridioides difficile is perfectly equipped to survive and persist
inside the mammalian intestine. When facing unfavorable conditions C. difficile is able to …