LINE-1 protein localization and functional dynamics during the cell cycle

P Mita, A Wudzinska, X Sun, J Andrade, S Nayak… - Elife, 2018 - elifesciences.org
LINE-1/L1 retrotransposon sequences comprise 17% of the human genome. Among the
many classes of mobile genetic elements, L1 is the only autonomous retrotransposon that …

Condensation of LINE-1 is critical for retrotransposition

S Sil, S Keegan, F Ettefa, LT Denes, JD Boeke, LJ Holt - Elife, 2023 - elifesciences.org
Abstract LINE-1 (L1) is the only autonomously active retrotransposon in the human genome,
and accounts for 17% of the human genome. The L1 mRNA encodes two proteins, ORF1p …

[图书][B] Condensation of LINE-1 is required for retrotransposition

S Sil - 2022 - search.proquest.com
Retrotransposons are DNA sequences that are able to “copy and paste” themselves in the
genome using an RNA intermediate. LINE-1 (L1) is the only autonomously active …

Generalized nuclear localization of retroelement transcripts

S Das, AE Jones, JM Abrams - Mobile DNA, 2022 - Springer
Background LINE-1s, Alus and SVAs are the only retrotransposition competent elements in
humans. Their mobilization followed by insertional mutagenesis is often linked to disease …

[图书][B] Single-stranded RNA phages: From molecular biology to nanotechnology

P Pumpens - 2020 - taylorfrancis.com
This is a comprehensive guide to single-stranded RNA phages (family Leviviridae), first
discovered in 1961. These phages played a unique role in early studies of molecular …

Étude du rôle pathogénique de la protéine ORF1p du rétrotransposon LINE-1 ciblant l'enveloppe nucléaire

R Znaidi - 2023 - theses.hal.science
Les éléments transposables (ET) ont émergé récemment comme un des moteurs du
vieillissement cellulaire et de la neurodégénérescence. En effet, ils sont apparus comme …

Transcriptional and Post-Transcriptional Regulation of Retroelements

S Das - 2022 - utswmed-ir.tdl.org
Retroelements make up nearly 40% of the human genome. Their ability to mobilize and
cause insertional mutagenesis makes them potentially harmful. Dysregulated retroelements …

L1 retrotransposon activity in muscle cells

PP Lopez - 2020 - theses.hal.science
Almost half of the human genome derives from transposable elements (TE). Among them,
the Long INterspersed Element-1 (LINE-1 or L1) forms the only currently active and …

Activité du rétrotransposon L1 dans les cellules musculaires

PP Lopez - 2020 - theses.fr
Près de la moitié du génome humain provient d'éléments transposables (TE). Parmi eux,
l'élément LINE-1 ou L1 (Long INterspersed Element-1) forme la seule famille d'éléments …

LINE-1 and the cell cycle: protein localization and functional dynamics

P Mita, A Wudzinska, X Sun, J Andrade, S Nayak… - bioRxiv, 2017 - biorxiv.org
Abstract LINE-1/L1 retrotransposon sequences comprise 17% of the human genome.
Among the many classes of mobile genetic elements, L1 is the only autonomous …