Abstract LINE-1 (L1) is the only autonomously active retrotransposon in the human genome, and accounts for 17% of the human genome. The L1 mRNA encodes two proteins, ORF1p …
Retrotransposons are DNA sequences that are able to “copy and paste” themselves in the genome using an RNA intermediate. LINE-1 (L1) is the only autonomously active …
S Das, AE Jones, JM Abrams - Mobile DNA, 2022 - Springer
Background LINE-1s, Alus and SVAs are the only retrotransposition competent elements in humans. Their mobilization followed by insertional mutagenesis is often linked to disease …
This is a comprehensive guide to single-stranded RNA phages (family Leviviridae), first discovered in 1961. These phages played a unique role in early studies of molecular …
Les éléments transposables (ET) ont émergé récemment comme un des moteurs du vieillissement cellulaire et de la neurodégénérescence. En effet, ils sont apparus comme …
Retroelements make up nearly 40% of the human genome. Their ability to mobilize and cause insertional mutagenesis makes them potentially harmful. Dysregulated retroelements …
Almost half of the human genome derives from transposable elements (TE). Among them, the Long INterspersed Element-1 (LINE-1 or L1) forms the only currently active and …
Près de la moitié du génome humain provient d'éléments transposables (TE). Parmi eux, l'élément LINE-1 ou L1 (Long INterspersed Element-1) forme la seule famille d'éléments …
P Mita, A Wudzinska, X Sun, J Andrade, S Nayak… - bioRxiv, 2017 - biorxiv.org
Abstract LINE-1/L1 retrotransposon sequences comprise 17% of the human genome. Among the many classes of mobile genetic elements, L1 is the only autonomous …