Urinary markers of tubular injury in early diabetic nephropathy

T Fiseha, Z Tamir - International journal of nephrology, 2016 - Wiley Online Library
Diabetic nephropathy (DN) is a common and serious complication of diabetes associated
with adverse outcomes of renal failure, cardiovascular disease, and premature mortality …

Urinary biomarkers for early diabetic nephropathy in type 2 diabetic patients

T Fiseha - Biomarker research, 2015 - Springer
Diabetic nephropathy (DN) is a serious complication of diabetes associated with increased
risk of mortality, and cardiovascular and renal outcomes. Diagnostic markers to detect DN at …

Novel insights into the pathophysiology and clinical aspects of diabetic nephropathy

Z Ilyas, JT Chaiban, A Krikorian - Reviews in Endocrine and Metabolic …, 2017 - Springer
Diabetic nephropathy (DN) is a well-described complication of diabetes mellitus and the
leading cause of end stage renal disease (ESRD). Although increased albuminuria has …

The promise of mesenchymal stem cell therapy for diabetic kidney disease

TP Griffin, WP Martin, N Islam, T O'Brien… - Current diabetes …, 2016 - Springer
Diabetes mellitus (DM) commonly leads to progressive chronic kidney disease despite
current best medical practice. The pathogenesis of diabetic kidney disease (DKD) involves a …

Multiplex bead array assay of a panel of circulating cytokines and growth factors in patients with albuminuric and non-albuminuric diabetic kidney disease

VV Klimontov, AI Korbut, NB Orlov, MV Dashkin… - Journal of Clinical …, 2020 - mdpi.com
A panel of cytokines and growth factors, mediating low-grade inflammation and fibrosis, was
assessed in patients with type 2 diabetes (T2D) and different patterns of chronic kidney …

Identification of Serum metabolites for predicting chronic kidney disease progression according to chronic kidney disease cause

E Kang, Y Li, B Kim, KY Huh, M Han, JH Ahn, HY Sung… - Metabolites, 2022 - mdpi.com
Early detection and proper management of chronic kidney disease (CKD) can delay
progression to end-stage kidney disease. We applied metabolomics to discover novel …

Diabetic kidney disease in older people with type 2 diabetes mellitus: improving prevention and treatment options

AH Abdelhafiz - Drugs & Aging, 2020 - Springer
Age-related metabolic and renal changes predispose older people to an increased risk of
diabetes mellitus and diabetic kidney disease, respectively. As the prevalence of the ageing …

Urinary heme oxygenase‐1 as a potential biomarker for early diabetic nephropathy

Z Li, Y Xu, X Liu, Y Nie, Z Zhao - Nephrology, 2017 - Wiley Online Library
Background Our previous study showed that increases of urinary heme oxygenase‐1 (uHO‐
1) could be a potential biomarker indicating evaluating intrarenal oxidative damage in …

A GC‐MS‐based metabolomics investigation of the protective effect of Liu‐Wei‐Di‐Huang‐wan in type 2 diabetes mellitus mice

J Huang, D He, L Chen, Q Du, R Yu… - … Journal of Analytical …, 2020 - Wiley Online Library
Aim of the Study. The present study aimed to establish a metabolic profile and to investigate
the changes of endogenous metabolites in diabetic mice treated with LWDHW. We further …

Association of neutrophil-gelatinase-associated lipocalin with microvascular complications in patients with type 2 diabetes: a cross-sectional study

E Aslanhan, D Ojalvo, EB Özsenel… - Cardiovascular …, 2019 - journals.lww.com
Results There were no significant differences in serum and urine NGAL levels between
normoalbuminuric (n= 66) and microalbuminuric (n= 16) patients. We also did not find any …