Maternal immunity and the natural history of congenital human cytomegalovirus infection

WJ Britt - Viruses, 2018 - mdpi.com
Congenital human cytomegalovirus (HCMV) is the most common viral infection of the
developing fetus, and a significant cause of neurodevelopmental abnormalities in infants …

Immune surveillance of cytomegalovirus in tissues

A Mihalić, J Železnjak, B Lisnić, S Jonjić… - Cellular & molecular …, 2024 - nature.com
Cytomegalovirus (CMV), a representative member of the Betaherpesvirinae subfamily of
herpesviruses, is common in the human population, but immunocompetent individuals are …

CD4+ T follicular helper cells in human tonsils and blood are clonally convergent but divergent from non-Tfh CD4+ cells

E Brenna, AN Davydov, K Ladell, JE McLaren… - Cell reports, 2020 - cell.com
T follicular helper (Tfh) cells are fundamental for B cell selection and antibody maturation in
germinal centers. Circulating Tfh (cTfh) cells constitute a minor proportion of the CD4+ T …

The CD4+ T cell response to human cytomegalovirus in healthy and immunocompromised people

EY Lim, SE Jackson, MR Wills - Frontiers in cellular and infection …, 2020 - frontiersin.org
While CD8+ T cells specific for human cytomegalovirus (HCMV) have been extensively
studied in both healthy HCMV seropositive carriers and patients undergoing …

[PDF][PDF] Human cytomegalovirus (HCMV) infection/re-infection: development of a protective HCMV vaccine

G Gerna, D Lilleri - New Microbiol, 2019 - newmicrobiologica.org
Prof. Giuseppe Gerna E-mail: g. gerna@ smatteo. pv. it© 2019 by EDIMES-Edizioni
Internazionali Srl. All rights reserved is primary infection of a seronegative pregnant mother …

Immune correlates of protection against human cytomegalovirus acquisition, replication, and disease

CS Nelson, I Baraniak, D Lilleri… - The Journal of …, 2020 - academic.oup.com
Human cytomegalovirus (HCMV) is the most common infectious cause of infant birth defects
and an etiology of significant morbidity and mortality in solid organ and hematopoietic stem …

Human cytomegalovirus (HCMV) long-term shedding and HCMV-specific immune response in pregnant women with primary HCMV infection

C Fornara, F Zavaglio, M Furione, A Sarasini… - Medical Microbiology …, 2022 - Springer
Human cytomegalovirus (HCMV) shedding has been extensively investigated in newborns
and in young children, however, much less is known about it in immunocompetent adults …

Performance of Zika assays in the context of Toxoplasma gondii, parvovirus B19, rubella virus, and cytomegalovirus (TORCH) diagnostic assays

B Voordouw, B Rockx, T Jaenisch, P Fraaij… - Clinical microbiology …, 2019 - Am Soc Microbiol
Infections during pregnancy that may cause congenital abnormalities have been recognized
for decades, but their diagnosis is challenging. This was again illustrated with the …

Congenital human cytomegalovirus infection: a narrative review of maternal immune response and diagnosis in view of the development of a vaccine and prevention …

G Gerna, C Fornara, M Furione, D Lilleri - Microorganisms, 2021 - mdpi.com
Congenital cytomegalovirus infection (cCMV) may affect about 1% of all newborns all over
the world as a result of either a primary or recurrent human cytomegalovirus (HCMV) …

Integrated immune monitoring of HCMV infection in pregnant women with complications and its association with adverse pregnancy outcomes

HC Palav, G Bhonde, V Padwal, S Velhal, J Pereira… - Microbial …, 2023 - Elsevier
Human Cytomegalovirus (HCMV) infection is associated with bad obstetric history (BOH)
and adverse pregnancy outcomes (APO). Here, we characterized antiviral humoral profiles …