The health burden of ischemic stroke is high and will continue to increase with an aging
population. Recurrent ischemic stroke is increasingly recognized as a major public health …

Antiplatelet therapy plays a critical role in the prevention and treatment of major
cardiovascular diseases triggered by thrombosis. Since the 1900s, significant progress in …

Surgical revascularization remains the standard treatment for symptomatic moyamoya
disease (MMD). As with any major surgical treatment, revascularization is associated with …

Background The combination of rivaroxaban plus aspirin compared with aspirin alone
reduces the risk of major adverse cardiovascular and limb events for high-risk patients with …

We determined the associations of follow-up blood pressure (BP) after stroke as a time-
dependent covariate with the risk of subsequent ischemic stroke, as well as those of BP …

Acetylsalicylic acid (ASA) represents a cornerstone of antiplatelet therapy for the treatment of
atherosclerotic coronary artery disease (CAD). ASA is in fact indicated in case of an acute …

Background Intestinal barrier dysfunction, which is associated with reactive enteric glia cells
(EGCs), is not only a result of early sepsis but also a cause of multiple organ dysfunction …

Background and Objectives Long-term treatment with the combination of cilostazol with
aspirin or clopidogrel showed a lower risk of stroke recurrence compared to aspirin or …

Abstract Background and Aims Patients with heart failure with preserved ejection fraction
(HFpEF) tend to have low resting and exercise heart rates. Phosphodiesterase‐3 (PDE‐3) …

Endothelial senescence, aging-related inflammation, and mitochondrial dysfunction are
prominent features of vascular aging and contribute to the development of aging-associated …