Prognostic significance of BIRC5/Survivin in breast cancer: results from three independent cohorts
Simple Summary Survivin, coded by the BIRC5 gene, is the cell death preventing protein,
which is important for cell division in normal and cancer cells. It is intensively studied as a …
which is important for cell division in normal and cancer cells. It is intensively studied as a …
Cancer Resistance Is Mediated by the Upregulation of Several Anti-Apoptotic Gene Products via the Inducible Nitric Oxide Synthase/Nitric Oxide Pathway …
Significance: Several therapeutic strategies for cancer treatments have been developed with
time, and significant milestones have been achieved recently. However, with these novel …
time, and significant milestones have been achieved recently. However, with these novel …
A systematic review of candidate genes and their relevant pathways for metastasis among adults diagnosed with breast cancer
GM Gehling, M Alfaqih, L Pruinelli… - Breast Cancer …, 2024 - Springer
Background Presently incurable, metastatic breast cancer is estimated to occur in as many
as 30% of those diagnosed with early-stage breast cancer. Timely and accurate …
as 30% of those diagnosed with early-stage breast cancer. Timely and accurate …
BIRC5 Gene Polymorphisms Are Associated with a Higher Stage of Local and Regional Disease in Oral and Oropharyngeal Squamous Cell Carcinomas
Oral squamous cell carcinoma (OSCC) and oropharyngeal squamous cell carcinoma
(OPSCC) are the most common types of cancers in the head and neck region (HNSCC) …
(OPSCC) are the most common types of cancers in the head and neck region (HNSCC) …
A nucleus-targeting fluorescence probe for rapid diagnosis of colorectal cancer
Y Xue, J Chi, B Ning, L Cheng, W Wang, Q Meng… - Chemical Engineering …, 2024 - Elsevier
Due to non-specific signs in the early stage of colorectal cancers, most patients result in a
low early diagnosis rate. Survivin protein is upregulated in many malignant tumors, making it …
low early diagnosis rate. Survivin protein is upregulated in many malignant tumors, making it …
BIRC5 expression by race, age and clinical factors in breast cancer patients
Purpose Survivin/BIRC5 is a proliferation marker that is associated with poor prognosis in
breast cancer and an attractive therapeutic target. However, BIRC5 has not been well …
breast cancer and an attractive therapeutic target. However, BIRC5 has not been well …
Thorough statistical analyses of breast cancer co-methylation patterns
S Sun, J Dammann, P Lai, C Tian - BMC Genomic Data, 2022 - Springer
Background Breast cancer is one of the most commonly diagnosed cancers. It is associated
with DNA methylation, an epigenetic event with a methyl group added to a cytosine paired …
with DNA methylation, an epigenetic event with a methyl group added to a cytosine paired …
Evidence for familial clustering in breast cancer age of onset
Background Familial clustering of age at onset would have implications for both
personalized screening and aetiology, but has not been studied for breast cancer. Methods …
personalized screening and aetiology, but has not been studied for breast cancer. Methods …
Survivin, a Moonlighting Caspase Inhibitor and Potential Oncotherapeutic Target
Survivin, the smallest member of the inhibitor of apoptosis proteins (IAPs), is a potent
inhibitor of caspases, the proteases that execute apoptotic cell death. Survivin has an …
inhibitor of caspases, the proteases that execute apoptotic cell death. Survivin has an …
[PDF][PDF] Predicting factors and top gene identification for survival data of breast cancer.
For high-throughput research with biological data-sets generated sequentially or by
transcriptional micro-arrays, proteomics or other means, analytic techniques that address …
transcriptional micro-arrays, proteomics or other means, analytic techniques that address …