The regulation of hyphae growth in Candida albicans

H Chen, X Zhou, B Ren, L Cheng - Virulence, 2020 - Taylor & Francis
In the last decades, Candida albicans has served as the leading causal agent of life-
threatening invasive infections with mortality rates approaching 40% despite treatment …

An Update on Candida tropicalis Based on Basic and Clinical Approaches

DL Zuza-Alves, WP Silva-Rocha… - Frontiers in …, 2017 - frontiersin.org
Candida tropicalis has emerged as one of the most important Candida species. It has been
widely considered the second most virulent Candida species, only preceded by C. albicans …

Recent insights into Candida albicans biofilm resistance mechanisms

L Mathé, P Van Dijck - Current genetics, 2013 - Springer
Like other microorganisms, free-living Candida albicans is mainly present in a three-
dimensional multicellular structure, which is called a biofilm, rather than in a planktonic form …

Antibiofilm and antifungal activities of medium‐chain fatty acids against Candida albicans via mimicking of the quorum‐sensing molecule farnesol

JH Lee, YG Kim, SK Khadke, J Lee - Microbial Biotechnology, 2021 - Wiley Online Library
Candida biofilms are tolerant to conventional antifungal therapeutics and the host immune
system. The transition of yeast cells to hyphae is considered a key step in C. albicans biofilm …

Cross-feeding and interkingdom communication in dual-species biofilms of Streptococcus mutans and Candida albicans

H Sztajer, SP Szafranski, J Tomasch, M Reck… - The ISME …, 2014 - academic.oup.com
Polymicrobial biofilms are of large medical importance, but relatively little is known about the
role of interspecies interactions for their physiology and virulence. Here, we studied two …

Candida survival strategies

M Polke, B Hube, ID Jacobsen - Advances in Applied Microbiology, 2015 - Elsevier
Only few Candida species, eg, Candida albicans, Candida glabrata, Candida dubliniensis,
and Candida parapsilosis, are successful colonizers of a human host. Under certain …

Candida Biofilms: Development, Architecture, and Resistance

J Chandra, PK Mukherjee - Microbial Biofilms, 2015 - Wiley Online Library
The use of indwelling devices in current therapeutic practice is associated with hospital‐
acquired bloodstream and deep tissue infections (1). Transplantation medical procedures …

Candida albicans morphogenesis programs control the balance between gut commensalism and invasive infection

JN Witchley, P Penumetcha, NV Abon, CA Woolford… - Cell host & …, 2019 - cell.com
Candida albicans is a gut commensal and opportunistic pathogen. The transition between
yeast and invasive hyphae is central to virulence but has unknown functions during …

Circuit diversification in a biofilm regulatory network

MY Huang, CA Woolford, G May, CJ McManus… - PLoS …, 2019 - journals.plos.org
Genotype-phenotype relationships can vary extensively among members of a species. One
cause of this variation is circuit diversification, the alteration of gene regulatory relationships …

Highlights in pathogenic fungal biofilms

JDCO Sardi, NDS Pitangui… - Revista iberoamericana …, 2014 - Elsevier
A wide variety of fungi have demonstrated the ability to colonize surfaces and form biofilms.
Most studies on fungal biofilms have focused on Candida albicans and more recently …