Platelet refractoriness can represent a significant clinical problem that complicates the
provision of platelet transfusions, is associated with adverse clinical outcomes and …

In this prospective study, 26 consecutive patients being treated for haematological
malignancies receiving standard (ie non-leucocyte-depleted) blood components were …

Recent studies have shown that the incidence of alloimmunization due to repeated platelet
transfusions from random donors may be reduced by the use of leucocyte‐poor blood …

Refractoriness is a complication of multiple platelet transfusions in 30–70% of patients with
bone marrow failure. The major causes are HLA alloimmunisation and non-immune platelet …

A multi‐site clinical study compared platelets chosen for refractory patients by prospective
platelet crossmatching using stored donor platelets and HLA‐based selection. Seventy …

BACKGROUND: HLA‐C antigens have been thought to be of little significance in
determining the efficacy of platelet transfusions. However, six alloimmunized patients were …

Platelets can adhere to surfaces by forming pseudopods. This ability is made use of here to
simplify conventional platelet suspension immunofluorescence tests, since steps like serum …

Platelet refractoriness is the repeated failure to obtain satisfactory responses to platelet
transfusions. It is mainly due to shortened platelet survival associated with non‐immune …

Alloimmunization by platelet transfusions was studied in 154 patients with acute leukaemia.
17 patients had HLA antibodies at initial presentation induced by previous transfusions or …

Six patients, 4 with acute myeloid leukaemia and 2 with a myelodysplasia syndrome who
were refractory to random donor platelet transfusions and alloimmunized to human …