[HTML][HTML] Nanocarriers for pancreatic cancer imaging, treatments, and immunotherapies

L Liu, PG Kshirsagar, SK Gautam, M Gulati, EI Wafa… - Theranostics, 2022 - ncbi.nlm.nih.gov
Pancreatic tumors are highly desmoplastic and immunosuppressive. Delivery and
distribution of drugs within pancreatic tumors are compromised due to intrinsic physical and …

Mucoadhesive polymers in the design of nano-drug delivery systems for administration by non-parenteral routes: A review

A Sosnik, J das Neves, B Sarmento - Progress in Polymer Science, 2014 - Elsevier
The presence of a mucus layer that covers the surface of a variety of organs has been
capitalized to develop mucoadhesive dosage forms that remain in the administration site for …

Glycopolymer-functionalized MOF-808 nanoparticles as a cancer-targeted dual drug delivery system for carboplatin and floxuridine

F Demir Duman, A Monaco, R Foulkes… - ACS Applied Nano …, 2022 - ACS Publications
Codelivery of chemotherapeutics via nanomaterials has attracted much attention over the
last decades due to improved drug delivery to tumor tissues, decreased systemic effects …

Glycopolymers for drug delivery: opportunities and challenges

MH Stenzel - Macromolecules, 2022 - ACS Publications
Glycopolymers are synthetic polymers with pendant sugars, which hold promise for a range
of biomedical applications ranging from tissue engineering to sensing. The known specific …

Glycopolymer probes of signal transduction

LL Kiessling, JC Grim - Chemical Society Reviews, 2013 - pubs.rsc.org
Glycans are key participants in biological processes ranging from reproduction to cellular
communication to infection. Revealing glycan roles and the underlying molecular …

Immunogene therapy with fusogenic nanoparticles modulates macrophage response to Staphylococcus aureus

B Kim, HB Pang, J Kang, JH Park, E Ruoslahti… - Nature …, 2018 - nature.com
The incidence of adverse effects and pathogen resistance encountered with small molecule
antibiotics is increasing. As such, there is mounting focus on immunogene therapy to …

Targeted drug delivery to macrophages

NK Jain, V Mishra, NK Mehra - Expert opinion on drug delivery, 2013 - Taylor & Francis
Introduction: Targeted drug delivery to the macrophages appears to be an attractive
proposition to improve therapeutic efficacy of enclosed drug. Thus, macrophages can be …

[HTML][HTML] Biomedical applications of polymers derived by reversible addition–fragmentation chain-transfer (RAFT)

BD Fairbanks, PA Gunatillake, L Meagher - Advanced drug delivery reviews, 2015 - Elsevier
RAFT-mediated polymerization, providing control over polymer length and architecture as
well as facilitating post polymerization modification of end groups, has been applied to …

Carbohydrate-based nanocarriers and their application to target macrophages and deliver antimicrobial agents

T Mosaiab, DC Farr, MJ Kiefel, TA Houston - Advanced drug delivery …, 2019 - Elsevier
Many deadly infections are produced by microorganisms capable of sustained survival in
macrophages. This reduces exposure to chemadrotherapy, prevents immune detection, and …

Glycocalyx‐mimicking nanoparticles for stimulation and polarization of macrophages via specific interactions

L Su, W Zhang, X Wu, Y Zhang, X Chen, G Liu, G Chen… - Small, 2015 - Wiley Online Library
Malignant tumors develop multiple mechanisms to impair and escape from antitumor
immune responses, of which tumor‐associated macrophages that often show …