Piano stool Ru (II)-arene complexes having three monodentate legs: A comprehensive review on their development as anticancer therapeutics over the past decade
The popularity of RAPTA-C in in vivo studies has steered the way for complexes of the type
[Ru (η 6-arene)(X)(Y)(Z)] n+ (where X, Y and Z are monodentate ligands) to be developed …
[Ru (η 6-arene)(X)(Y)(Z)] n+ (where X, Y and Z are monodentate ligands) to be developed …
Design concepts of half-sandwich organoruthenium anticancer agents based on bidentate bioactive ligands
The small molecule anticancer agent cisplatin and its Pt (II) analogs carboplatin and
oxaliplatin are widely used to treat a variety of tumorigenic diseases. Despite their structural …
oxaliplatin are widely used to treat a variety of tumorigenic diseases. Despite their structural …
Synthesis and Structure of Arene Ru(II) N∧O-Chelating Complexes: In Vitro Cytotoxicity and Cancer Cell Death Mechanism
A panel of six new structurally related organometallic arene Ru (II) complexes of general
composition [(η6-benzene) Ru (L) Cl](1–3) and [(η6-p-cymene) Ru (L) Cl](4–6)(L …
composition [(η6-benzene) Ru (L) Cl](1–3) and [(η6-p-cymene) Ru (L) Cl](4–6)(L …
Novel tetranuclear ruthenium (II) arene complexes showing potent cytotoxic and antimetastatic activity as well as low toxicity in vivo
MKM Subarkhan, L Ren, B Xie, C Chen, Y Wang… - European journal of …, 2019 - Elsevier
Ruthenium complexes have attracted a surge of interest as anticancer drug candidates
because of their low toxicity, diversity in mode-of-actions and non-cross drug resistance with …
because of their low toxicity, diversity in mode-of-actions and non-cross drug resistance with …
Synthesis and structure of new binuclear ruthenium (II) arene benzil bis (benzoylhydrazone) complexes: investigation on antiproliferative activity and apoptosis …
MSM Kasim, S Sundar, R Rengan - Inorganic chemistry frontiers, 2018 - pubs.rsc.org
A series of binuclear ruthenium (II) arene benzil bis (benzoylhydrazone) complexes (1–6) of
the common composition [(η6-arene) 2Ru2 (L) Cl2](arene= benzene or p-cymene; L= benzil …
the common composition [(η6-arene) 2Ru2 (L) Cl2](arene= benzene or p-cymene; L= benzil …
Construction of homo and heteronuclear Ru (II), Ir (III) and Re (I) complexes for target specific cancer therapy
More than 10 million death tolls in 2020 were reported as a result of heinous impact of
cancer, making it second most prime cause of death after cardiovascular diseases. In …
cancer, making it second most prime cause of death after cardiovascular diseases. In …
Antiproliferative activity of chelating N, O-and N, N-ruthenium (II) arene functionalised poly (propyleneimine) dendrimer scaffolds
Chelating neutral (N, O) and cationic (N, N) first-and second-generation ruthenium (II) arene
metallodendrimers based on poly (propyleneimine) dendrimer scaffolds were obtained from …
metallodendrimers based on poly (propyleneimine) dendrimer scaffolds were obtained from …
Recent advances in cytotoxicity, cellular uptake and mechanism of action of ruthenium metallodrugs: A review
Due to these limitations of platinum-based drugs, it has now become a challenge for
researchers to find out a potential scaffold furnished with indispensable properties like …
researchers to find out a potential scaffold furnished with indispensable properties like …
Tuning the cytotoxicity of ruthenium (II) para-cymene complexes by mono-substitution at a triphenylphosphine/phenoxydiphenylphosphine ligand
L Biancalana, S Zacchini, N Ferri, MG Lupo… - Dalton …, 2017 - pubs.rsc.org
The new complexes [RuCl2 (η6-p-cymene)(κP-Ph2PR)][R= 4-C6H4OSiMe2tBu, 1; R= 4-
C6H4Br, 2; R= OC (O) CHCl2, 3; R= OPh, 4; R= O (2-C6H4SiMe2tBu), 5] and [Ru (C2O4)(η6 …
C6H4Br, 2; R= OC (O) CHCl2, 3; R= OPh, 4; R= O (2-C6H4SiMe2tBu), 5] and [Ru (C2O4)(η6 …
Synthesis and antiproliferative activity of new ruthenium complexes with ethacrynic-acid-modified pyridine and triphenylphosphine ligands
G Agonigi, T Riedel, S Zacchini, E Paunescu… - Inorganic …, 2015 - ACS Publications
Pyridine-and phosphine-based ligands modified with ethacrynic acid (a broad acting
glutathione transferase inhibitor) were prepared and coordinated to ruthenium (II)–arene …
glutathione transferase inhibitor) were prepared and coordinated to ruthenium (II)–arene …