Myofibroblasts are the construction workers of wound healing and repair damaged tissues
by producing and organizing collagen/extracellular matrix (ECM) into scar tissue. Scar tissue …

Physical stimuli are essential for the function of eukaryotic cells, and changes in physical
signals are important elements in normal tissue development as well as in disease initiation …

Metastasis causes most cancer-related deaths; however, the efficacy of anti-metastatic drugs
is limited by incomplete understanding of the biological mechanisms that drive metastasis …

The physical characteristics of tumours are intricately linked to the tumour phenotype and
difficulties during treatment. Many factors contribute to the increased stiffness of tumours; …

Taxis orientation is common in microorganisms, and it provides feasible strategies to
operate active colloids as small‐scale robots. Collective taxes involve numerous units that …

In many cancers, tumour progression is associated with increased tissue stiffness. Yet, the
mechanisms associating tissue stiffness with tumorigenesis and malignant transformation …

Breast cancer development is associated with increasing tissue stiffness over years. To
more accurately mimic the onset of gradual matrix stiffening, which is not feasible with …

The extracellular matrix (ECM) is pivotal in modulating tumor progression. Besides
chemically stimulating tumor cells, it also offers physical support that orchestrates the …

Communities of epithelial cells communicate through intercellular interactions, allowing
them to coordinate their motility, which plays a key role in homeostasis, morphogenesis and …

The ability to maintain and differentiate cells in vitro is critical to many advances in the field
of bioengineering. However, on traditional, stiff (E≈ GPa) culture substrates, cells are …