Sickle cell disease (SCD) or homozygous sickle cell anemia is the most common inherited
disorder of erythrocytes, characterized by the presence of pathologic hemoglobin S (HbS). A …

Sickle hepatopathy is an umbrella term describing various pattern of liver injury seen in
patients with sickle cell disease. The disease is not uncommon in India; in terms of …

Sickle cell disease (SCD) has a distinct pattern of transfusional iron overload (IO) when
compared to transfusion‐dependent β‐thalassaemia major (TDT). We conducted a single …

Liver involvement in sickle cell disease (SCD) is often referred to as sickle cell hepatopathy
(SCH) and is a complication of SCD which may be associated with significant mortality. This …

Sickle cell disease (SCD) is an autosomal recessive genetic disorder that affects∼ 100,000
Americans and millions of people worldwide. Erythrocyte sickling, vaso-occlusion, sterile …

Liver disease is an important cause of morbidity and mortality in patients with sickle cell
disease (SCD). Despite this, the natural history of liver disease is not well characterized and …

The hepatic complications of sickle cell disease (SCD) are associated with increased
morbidity and mortality in adults; children usually survive but may suffer significant sequelae …

Sickle hepatopathy is a severe and not rare complication of sickle cell disease (SCD),
showing mainly a cholestatic pattern. So far, no effective approaches to prevent or treat this …

Purpose Patients who receive frequent blood transfusions are at an elevated risk of
developing hepatic fibrosis due to iron overload in the liver. In this study, we evaluated the …

Vibration controlled transient elastography (VCTE) is validated for the evaluation of hepatic
fibrosis in different liver diseases. Sickle cell liver disease (SCLD) results from a cumulative …