[HTML][HTML] Simulation-based approaches for drug delivery systems: Navigating advancements, opportunities, and challenges

I Salahshoori, M Golriz, MAL Nobre, S Mahdavi… - Journal of Molecular …, 2024 - Elsevier
Efficient drug delivery systems (DDSs) play a pivotal role in ensuring pharmaceuticals'
targeted and effective administration. However, the intricate interplay between drug …

Development and validation of an explainable machine learning-based prediction model for drug–food interactions from chemical structures

QH Kha, VH Le, TNK Hung, NTK Nguyen, NQK Le - Sensors, 2023 - mdpi.com
Possible drug–food constituent interactions (DFIs) could change the intended efficiency of
particular therapeutics in medical practice. The increasing number of multiple-drug …

Enzyme-mediated drug-drug interactions: a review of in vivo and in vitro methodologies, regulatory guidance, and translation to the clinic

J Yadav, BJ Maldonato, JM Roesner… - Drug Metabolism …, 2024 - Taylor & Francis
Enzyme-mediated pharmacokinetic drug-drug interactions can be caused by altered activity
of drug metabolizing enzymes in the presence of a perpetrator drug, mostly via inhibition or …

A survey of the recent trends in deep learning for literature based discovery in the biomedical domain

E Cesario, C Comito, E Zumpano - Neurocomputing, 2024 - Elsevier
Every day, enormous amounts of biomedical texts discussing various biomedical topics are
produced. Revealing strong semantic connections hidden in those unstructured data is …

Multimodal CNN-DDI: using multimodal CNN for drug to drug interaction associated events

M Asfand-E-Yar, Q Hashir, AA Shah, HAM Malik… - Scientific Reports, 2024 - nature.com
Drug-to-drug interaction (DDIs) occurs when a patient consumes multiple drugs. Therefore, it
is possible that any medication can influence other drugs' effectiveness. The drug-to-drug …

DBGRU-SE: predicting drug–drug interactions based on double BiGRU and squeeze-and-excitation attention mechanism

M Zhang, H Gao, X Liao, B Ning, H Gu… - Briefings in …, 2023 - academic.oup.com
The prediction of drug–drug interactions (DDIs) is essential for the development and
repositioning of new drugs. Meanwhile, they play a vital role in the fields of …

Fsrm-ddie: few-shot learning methods based on relation metrics for the prediction of drug-drug interaction events

L Zhang, D Niu, B Zhang, Q Zhang, Z Li - Applied Intelligence, 2024 - Springer
Drug-drug interaction (DDI) prediction aims to predict and evaluate potential interactions
between different drugs, assisting healthcare professionals in optimizing drug therapy …

A novel drug-drug indicator dataset and ensemble stacking model for detection and classification of drug-drug interaction indicators

S Abbas, GA Sampedro, M Abisado… - IEEE …, 2023 - ieeexplore.ieee.org
Drug-drug interaction (DDI) is a significant public health issue that accounts for 30% of
unanticipated clinically hazardous medication events. The past decade has seen an …

An NLP-based technique to extract meaningful features from drug SMILES

R Sharma, E Saghapour, JY Chen - Iscience, 2024 - cell.com
NLP is a well-established field in ML for developing language models that capture the
sequence of words in a sentence. Similarly, drug molecule structures can also be …

[HTML][HTML] GADNN: A graph attention-based method for drug-drug association prediction considering the contribution rate of different types of drug-related features

M Nejati, A Lakizadeh - Informatics in Medicine Unlocked, 2024 - Elsevier
The simultaneous use of multiple drugs, known as drug combinations, is increasingly
common in the treatment of complex diseases such as cancer. However, drug-drug …