GTPase networks in membrane traffic
E Mizuno-Yamasaki, F Rivera-Molina… - Annual review of …, 2012 - annualreviews.org
Members of the Rab or ARF/Sar branches of the Ras GTPase superfamily regulate almost
every step of intracellular membrane traffic. A rapidly growing body of evidence indicates …
every step of intracellular membrane traffic. A rapidly growing body of evidence indicates …
Nonmuscle myosin-2: mix and match
SM Heissler, DJ Manstein - Cellular and Molecular Life Sciences, 2013 - Springer
Members of the nonmuscle myosin-2 (NM-2) family of actin-based molecular motors
catalyze the conversion of chemical energy into directed movement and force thereby acting …
catalyze the conversion of chemical energy into directed movement and force thereby acting …
Chromosomal 3q amplicon encodes essential regulators of secretory vesicles that drive secretory addiction in cancer
Cancer cells exhibit heightened secretory states that drive tumor progression. Here, we
identified a chromosome 3q amplicon that serves as a platform for secretory regulation in …
identified a chromosome 3q amplicon that serves as a platform for secretory regulation in …
Cohen syndrome-associated protein, COH1, is a novel, giant Golgi matrix protein required for Golgi integrity
W Seifert, J Kühnisch, T Maritzen, D Horn… - Journal of Biological …, 2011 - ASBMB
Loss-of-function mutations in the gene COH1, also known as VPS13B, lead to autosomal
recessive Cohen syndrome. However, the cellular distribution and function of the encoded …
recessive Cohen syndrome. However, the cellular distribution and function of the encoded …
Rab proteins as major determinants of the Golgi complex structure
ABSTRACT GTP-ases of the Rab family (about 70 in human) are key regulators of
intracellular transport and membrane trafficking in eukaryotic cells. Remarkably, almost one …
intracellular transport and membrane trafficking in eukaryotic cells. Remarkably, almost one …
Arabidopsis RABA1 GTPases are involved in transport between the trans‐Golgi network and the plasma membrane, and are required for salinity stress tolerance
R Asaoka, T Uemura, J Ito, M Fujimoto, E Ito… - The Plant …, 2013 - Wiley Online Library
RAB GTP ases are key regulators of membrane traffic. Among them, RAB 11, a widely
conserved sub‐group, has evolved in a unique way in plants; plant RAB 11 members show …
conserved sub‐group, has evolved in a unique way in plants; plant RAB 11 members show …
Are Rab proteins the link between Golgi organization and membrane trafficking?
The fundamental separation of Golgi function between subcompartments termed cisternae is
conserved across all eukaryotes. Likewise, Rab proteins, small GTPases of the Ras …
conserved across all eukaryotes. Likewise, Rab proteins, small GTPases of the Ras …
Rab35 promotes the recruitment of Rab8, Rab13 and Rab36 to recycling endosomes through MICAL-L1 during neurite outgrowth
H Kobayashi, K Etoh, N Ohbayashi… - Biology open, 2014 - journals.biologists.com
ABSTRACT Small GTPase Rab35 is an important molecular switch for endocytic recycling
that regulates various cellular processes, including cytokinesis, cell migration, and neurite …
that regulates various cellular processes, including cytokinesis, cell migration, and neurite …
Phenome-based approach identifies RIC1-linked Mendelian syndrome through zebrafish models, biobank associations and clinical studies
Discovery of genotype–phenotype relationships remains a major challenge in clinical
medicine. Here, we combined three sources of phenotypic data to uncover a new …
medicine. Here, we combined three sources of phenotypic data to uncover a new …
Rab6-mediated retrograde trafficking from the Golgi: the trouble with tubules
L G. Dornan, J C. Simpson - Small GTPases, 2023 - Taylor & Francis
Next year marks one-quarter of a century since the discovery of the so-called COPI-
independent pathway, which operates between the Golgi apparatus and the endoplasmic …
independent pathway, which operates between the Golgi apparatus and the endoplasmic …