Background Kidney transplantation is the optimal treatment for end‐stage kidney disease.
Retrieval, transport and transplant of kidney grafts causes ischaemia reperfusion injury. The …

Many factors influence the long‐term outcome of kidney transplantation, which is defined
very schematically by patient death or renal dysfunction leading to graft loss. The most …

Cold static preservation on ice (~ 4° C) remains the clinical standard of donor organ
preservation. However, mitochondrial injury develops during prolonged storage, which limits …

In as many as 50% of cases the immediate post-kidney transplant course is complicated by
delayed graft function that is most commonly related to ischemia and reperfusion injury. In …

Background Adequate preservation of renal allografts for transplantation is important for
maintaining and improving transplant outcomes. There are two prevalent methods …

Solid organ transplantation was one of the greatest medical advances during the past few
decades. Organ preservation solutions have been applied to diminish ischemic/hypoxic …

Delayed graft function (DGF) remains a major barrier to improved outcomes after kidney
transplantation. High‐risk transplant recipients can be identified, but no definitive prediction …

Background Lung transplantation is performed on a 24/7 schedule to minimize organ
ischemic time. Recent preclinical studies demonstrated superior graft preservation at 10° C …

The use of cold preservation solutions to rapidly flush and cool the kidney followed by static
cold storage in ice has been the standard kidney preservation technique for the last 50 y …

The high demand for organs in kidney transplantation and the expansion of the donor pool
have led to the widespread implementation of machine perfusion technologies. In this study …