Phytochemicals belonging to the group of alkaloids are signature specialized metabolites
endowed with countless biological activities. Plants are armored with these naturally …

As the world endures the coronavirus disease 2019 (COVID-19) pandemic, the conditions of
35 million vulnerable individuals struggling with substance use disorders (SUDs) worldwide …

Blood–brain barrier pathology is recognised as a central factor in the development of many
neurological disorders, but much less is known about the role of the blood–brain barrier in …

The use of psychostimulants and alcohol disrupts blood-brain barrier (BBB) integrity,
resulting in alterations to cellular function, and contributes to neurotoxicity. The BBB is the …

Methamphetamine (METH) is a highly addictive drug abused by millions of users worldwide,
thus becoming a global health concern with limited management options. The inefficiency of …

The increasing incidence of autism suggests a major environmental influence. Epidemiology
has implicated many candidates and genetics many susceptibility genes. Gene/environment …

Traumatic brain injury (TBI) is among the most pressing global health issues and prevalent
causes of cerebrovascular and neurological disorders all over the world. In addition to the …

Neuroimaging studies in substance use disorder have shown widespread impairments in
white matter (WM) microstructure suggesting demyelination and axonal damage. However …

Antibodies against neuronal receptors and synaptic proteins are associated with
autoimmune encephalitides (AE) that produce movement and psychiatric disorders. In order …

Endothelial-mesenchymal transition (EndoMT) is associated with damage to blood-brain
barrier (BBB) integrity. Circular RNAs (circRNAs) are highly expressed in the brain and are …