Intestinal alkaline phosphatase: a summary of its role in clinical disease

J Fawley, DM Gourlay - Journal of Surgical Research, 2016 - Elsevier
Over the past few years, there is increasing evidence implicating a novel role for Intestinal
Alkaline Phosphatase (IAP) in mitigating inflammatory mediated disorders. IAP is an …

Testicular cancer biomarkers: a role for precision medicine in testicular cancer

R Leão, AE Ahmad, RJ Hamilton - Clinical genitourinary cancer, 2019 - Elsevier
Testicular germ cell tumors (TGCTs) represent the most common solid tumors among men
aged 15 to 34 years. Fortunately, recent advances have made testicular cancer a highly …

Serum tumour markers in testicular germ cell tumours: frequencies of elevated levels and extents of marker elevation are significantly associated with clinical …

KP Dieckmann, H Simonsen-Richter… - BioMed research …, 2019 - Wiley Online Library
Introduction. Although serum tumor markers beta human chorionic gonadotropin (bHCG),
alpha‐fetoprotein (AFP), and lactate dehydrogenase (LDH) are well‐established tools for …

Testicular germ-cell tumours: a descriptive analysis of clinical characteristics at first presentation

KP Dieckmann, H Richter-Simonsen… - Urologia …, 2018 - karger.com
Introduction: Clinical characteristics of testicular germ cell tumours (GCTs) apparently
change over time, and some vary geographically. The aim of this study is to document the …

Alkaline phosphatase ALPPL-2 is a novel pancreatic carcinoma-associated protein

P Dua, HS Kang, SM Hong, MS Tsao, S Kim, D Lee - Cancer research, 2013 - AACR
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy with a very
low median survival rate. The lack of early sensitive diagnostic markers is one of the main …

Alkaline phosphatase: a possible treatment for sepsis-associated acute kidney injury in critically ill patients

E Peters, S Heemskerk, R Masereeuw… - American Journal of …, 2014 - Elsevier
Acute kidney injury (AKI) is a common disease in the intensive care unit and accounts for
high morbidity and mortality. Sepsis, the predominant cause of AKI in this setting, involves a …

[HTML][HTML] The novel biomarker of germ cell tumours, micro-RNA-371a-3p, has a very rapid decay in patients with clinical stage 1

A Radtke, F Hennig, R Ikogho, J Hammel… - Urologia …, 2018 - karger.com
Background: Accumulating evidence suggests serum levels of microRNA (miR)-371a-3p to
be a novel tumour marker of testicular germ cell tumours (GCTs). Presently, there is only …

Production of newfound alkaline phosphatases from marine organisms with potential functions and industrial applications

S Sharifian, A Homaei, SK Kim, M Satari - Process Biochemistry, 2018 - Elsevier
The oceans have been shown as an almost entire reserve of novel enzymes. Alkaline
phosphatase (AP) is a key-enzyme in the marine environment. This review provides an …

Liquid biopsies in the clinical management of germ cell tumor patients: state-of-the-art and future directions

J Lobo, R Leão, C Jerónimo, R Henrique - International Journal of …, 2021 - mdpi.com
Liquid biopsies constitute a minimally invasive means of managing cancer patients,
entailing early diagnosis, follow-up and prediction of response to therapy. Their use in the …

[HTML][HTML] Serum levels of microRNA371a-3p: a highly sensitive tool for diagnosing and staging testicular germ cell tumours: a clinical case series

P Anheuser, A Radtke, C Wülfing, J Kranz… - Urologia …, 2017 - karger.com
Abstract Introduction: MicroRNA (miR) 371a-3p was suggested to be a sensitive and specific
new serum biomarker of germ cell tumours (GCTs); however, its clinical usefulness remains …