Precision public health (PPH) considers the interplay between genetics, lifestyle and the
environment to improve disease prevention, diagnosis and treatment on a population level …

Use of germline genetic testing among patients with cancer is increasing because of (1) the
availability of multigene panel tests that include multiple cancer susceptibility genes in a …

PURPOSE To develop recommendations for germline mutation testing for patients with
breast cancer. METHODS An ASCO–Society of Surgical Oncology (SSO) panel convened to …

Historically, professional society guidelines have recommended limited genetic testing for
hereditary cancer syndromes (HCS) to patients with cancer thought to be at highest risk for …

Background Germline risk assessment is increasing as part of cancer care; however,
disparities in subsequent genetic counseling are unknown. Methods Pan‐cancer patients …

Many countries currently invest in technologies and data infrastructures to foster precision
medicine (PM), which is hoped to better tailor disease treatment and prevention to individual …

Objective: The objective of this review was to map the available global evidence on
strategies that nurses can use to facilitate genomics-informed health care to address health …

TSC2 is a tumor suppressor gene as well as a disease-causing gene for autosomal
dominant disorder tuberous sclerosis complex (TSC). Research has found that some tumor …

In the era of precision medicine, genomic interrogation for identification of both germline and
somatic genetic alterations has become increasingly important. While such germline testing …

Background Clinical interpretation of genetic test results is complicated by variants of
uncertain significance (VUS) that have an unknown impact on health but can be clarified …