Adaptive deep brain stimulation: From experimental evidence toward practical implementation
WJ Neumann, R Gilron, S Little… - Movement …, 2023 - Wiley Online Library
Closed‐loop adaptive deep brain stimulation (aDBS) can deliver individualized therapy at
an unprecedented temporal precision for neurological disorders. This has the potential to …
an unprecedented temporal precision for neurological disorders. This has the potential to …
A systematic review of local field potential physiomarkers in Parkinson's disease: from clinical correlations to adaptive deep brain stimulation algorithms
BCM van Wijk, RMA de Bie, M Beudel - Journal of neurology, 2023 - Springer
Deep brain stimulation (DBS) treatment has proven effective in suppressing symptoms of
rigidity, bradykinesia, and tremor in Parkinson's disease. Still, patients may suffer from …
rigidity, bradykinesia, and tremor in Parkinson's disease. Still, patients may suffer from …
[HTML][HTML] Spectral and spatial distribution of subthalamic beta peak activity in Parkinson's disease patients
Current efforts to optimise subthalamic deep brain stimulation in Parkinson's disease
patients aim to harness local oscillatory activity in the beta frequency range (13–35 Hz) as a …
patients aim to harness local oscillatory activity in the beta frequency range (13–35 Hz) as a …
Combining multimodal biomarkers to guide deep brain stimulation programming in Parkinson disease
Background Deep brain stimulation (DBS) programming of multicontact DBS leads relies on
a very time-consuming manual screening procedure, and strategies to speed up this …
a very time-consuming manual screening procedure, and strategies to speed up this …
osl-dynamics, a toolbox for modeling fast dynamic brain activity
Neural activity contains rich spatiotemporal structure that corresponds to cognition. This
includes oscillatory bursting and dynamic activity that span across networks of brain regions …
includes oscillatory bursting and dynamic activity that span across networks of brain regions …
Controlling clinical states governed by different temporal dynamics with closed-loop deep brain stimulation: a principled framework
G Tinkhauser, EM Moraud - Frontiers in neuroscience, 2021 - frontiersin.org
Closed-loop strategies for deep brain stimulation (DBS) are paving the way for improving the
efficacy of existing neuromodulation therapies across neurological disorders. Unlike …
efficacy of existing neuromodulation therapies across neurological disorders. Unlike …
[HTML][HTML] Perspectives of implementation of closed-loop deep brain stimulation: from neurological to psychiatric disorders
S Groppa, G Gonzalez-Escamilla… - Stereotactic and …, 2024 - karger.com
Background: Deep brain stimulation (DBS) is a highly efficient, evidence-based therapy to
alleviate symptoms and improve quality of life in movement disorders such as Parkinson's …
alleviate symptoms and improve quality of life in movement disorders such as Parkinson's …
Spectral topography of the subthalamic nucleus to inform next‐generation deep brain stimulation
Background The landscape of neurophysiological symptoms and behavioral biomarkers in
basal ganglia signals for movement disorders is expanding. The clinical translation of …
basal ganglia signals for movement disorders is expanding. The clinical translation of …
[HTML][HTML] Auditory cues modulate the short timescale dynamics of STN activity during stepping in Parkinson's disease
Background Gait impairment has a major impact on quality of life in patients with Parkinson's
disease (PD). It is believed that basal ganglia oscillatory activity at β frequencies (15–30 Hz) …
disease (PD). It is believed that basal ganglia oscillatory activity at β frequencies (15–30 Hz) …
Pharmacological interventions targeting α-synuclein aggregation triggered REM sleep behavior disorder and early development of Parkinson's disease
L Du, X He, X Fan, X Wei, L Xu, T Liang, C Wang… - Pharmacology & …, 2023 - Elsevier
Rapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia characterized
by elevated motor behaviors and dream enactments in REM sleep, often preceding the …
by elevated motor behaviors and dream enactments in REM sleep, often preceding the …