Methods that enable rapid, sensitive and specific analyses of nucleic acid sequences have
positive effects on precise disease diagnostics and effective clinical treatments by providing …

Next-generation sequencing (NGS) technologies have revolutionized multiple areas in the
field of infectious diseases, from pathogen discovery to characterization of genes mediating …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein (S) plays
critical roles in host cell entry. Non-synonymous substitutions affecting S are not uncommon …

Since the beginning of the COVID-19 outbreak, SARS-CoV-2 whole-genome sequencing
(WGS) has been performed at unprecedented rate worldwide with the use of very diverse …

Background Myocarditis is an inflammatory disease of the myocardium, which leads to
cardiac dysfunction and heart failure. Previous studies have suggested that complex cross …

FDA proactively invests in tools to support innovation of emerging technologies, such as
infectious disease next generation sequencing (ID-NGS). Here, we introduce FDA-ARGOS …

Antimicrobial resistance (AMR) has become a global medical priority that needs urgent
resolution. Pseudomonas aeruginosa is a versatile, adaptable bacterial species with …

Objectives The purpose of this study was to explore the role of mNGS in the diagnosis of PJI
by detecting the presence of bacteria in periprosthetic tissues. Methods Patients who were …

We describe the most common internal and external sources and types of contamination
encountered in viral metagenomic studies and discuss their negative impact on sequencing …

Acute respiratory infection is the third most frequent cause of mortality worldwide, causing
over 4.25 million deaths annually. Although most diagnosed acute respiratory infections are …