Use it or lose it: multiscale skeletal muscle adaptation to mechanical stimuli

KM Wisdom, SL Delp, E Kuhl - Biomechanics and modeling in …, 2015 - Springer
Skeletal muscle undergoes continuous turnover to adapt to changes in its mechanical
environment. Overload increases muscle mass, whereas underload decreases muscle …

Botulinum toxin intervention in cerebral palsy-induced spasticity management: projected and contradictory effects on skeletal muscles

CS Kaya Keles, F Ates - Toxins, 2022 - mdpi.com
Spasticity, following the neurological disorder of cerebral palsy (CP), describes a
pathological condition, the central feature of which is involuntary and prolonged muscle …

Isoform diversity of giant proteins in relation to passive and active contractile properties of rabbit skeletal muscles

LG Prado, I Makarenko, C Andresen… - The Journal of general …, 2005 - rupress.org
The active and passive contractile performance of skeletal muscle fibers largely depends on
the myosin heavy chain (MHC) isoform and the stiffness of the titin spring, respectively. Open …

Gigantic variety: expression patterns of titin isoforms in striated muscles and consequences for myofibrillar passive stiffness

C Neagoe, CA Opitz, I Makarenko, WA Linke - Journal of Muscle Research …, 2003 - Springer
The giant muscle protein titin has become a focus of research interests in the field of muscle
mechanics due to its importance for passive muscle stiffness. Here we summarize research …

[HTML][HTML] Botulinum toxin intervention in cerebral palsy-induced spasticity management: projected and contradictory effects on skeletal muscles

CSK Keles, F Ates - Toxins, 2022 - ncbi.nlm.nih.gov
Spasticity, following the neurological disorder of cerebral palsy (CP), describes a
pathological condition, the central feature of which is involuntary and prolonged muscle …

Cellular responses of human postural muscle to dry immersion

BS Shenkman, IB Kozlovskaya - Frontiers in physiology, 2019 - frontiersin.org
Support withdrawal has been currently considered as one of the main factors involved in
regulation of the human locomotor system. For last decades, several authors, including the …

Calcium-dependent signaling mechanisms and soleus fiber remodeling under gravitational unloading

BS Shenkman, TL Nemirovskaya - Journal of muscle research and cell …, 2008 - Springer
The decrease in postural muscle fiber size, diminishing of their contractile properties, slow-to-
fast shift in myosin heavy chain expression pattern are known to be the main consequences …

Contractile and connective tissue protein content of human skeletal muscle: effects of 35 and 90 days of simulated microgravity and exercise countermeasures

JM Haus, JA Carrithers, CC Carroll… - American Journal …, 2007 - journals.physiology.org
We examined the effects of 35 and 90 days of simulated microgravity with or without
resistance-exercise (RE) countermeasures on the content of the general skeletal muscle …

Effects of exercise prehabilitation on muscle atrophy and contractile properties in hindlimb‐unloaded rats

HS Yeo, JY Lim - Muscle & Nerve, 2023 - Wiley Online Library
Abstract Introduction/Aims Effective strategies for rapid recovery after surgery are needed.
Therefore, we investigated the effects of exercise prehabilitation (EP) and hindlimb …

Transversal stiffness of fibers and desmin content in leg muscles of rats under gravitational unloading of various durations

IV Ogneva - Journal of Applied Physiology, 2010 - journals.physiology.org
The aim of this research was the analysis of structural changes in various parts of the
sarcolemma and contractile apparatus of muscle fibers by measuring their transversal …