MicroRNAs (miRNAs) are defined as small non-coding RNAs~ 22 nt in length. They regulate
gene expression at a post-transcriptional level through complementary base pairing with the …

Pregnancy complications are a major cause of fetal and maternal morbidity and mortality in
humans. The majority of pregnancy complications initiate due to abnormal placental …

Abstract microRNAs (miRNAs) are a class of endogenous short, non-coding RNAs that
regulate a multitude of genes at the post-transcriptional level. miR-199, which is a highly …

Glioblastoma (GBM) is one of the most devastating cancers and is characterized by rapid
cell proliferation and aggressive invasiveness. Legumain (LGMN), a substrate-specific …

MiRNAs post-transcriptionally repress gene expression by binding to mRNA 3′ UTRs, but
the extent to which they act through protein coding regions (CDS regions) is less well …

Accumulating evidence indicates noncoding RNAs (ncRNAs) fine-tune gene expression
with mysterious machinery. We conducted a combination of mRNA, miRNA, circRNA …

MicroRNAs (miRNAs) regulate a majority of protein-coding genes, affecting nearly all
biological pathways. However, the quantitative dimensions of miRNA-based regulation are …

SAMHD1 is a phosphohydrolase maintaining cellular dNTP homeostasis but also acts as a
critical regulator in innate immune responses due to its antiviral activity and association with …

The human UGT gene superfamily is divided into four subfamilies (UGT1, UGT2, UGT3 and
UGT8) that encodes 22 functional enzymes. UGTs are critical for the metabolism and …

Moulting is critical for growth, development and survival in insects. As the main components
of cuticle, dynamic change of chitin is consistent with the moulting process. Chitinase is the …