Background Infectious diseases are the leading cause of death in 21 st century due to
antimicrobial resistance and scarcity of new molecules to undertake rising infections. There …

Apigenin is a flavonoid of low toxicity and multiple beneficial bioactivities. Published reviews
all focused on the findings using eukaryotic cells, animal models, or epidemiological studies …

Effective control of oral biofilm infectious diseases represents a major global challenge.
Microorganisms in biofilms exhibit increased drug tolerance compared with planktonic cells …

Biofilms are microbial communities attached to a surface and embedded in an extracellular
polymeric substance which provides for the protection, stability and nutrients of the various …

Decreased antimicrobial efficiency has become a global public health issue. The paucity of
new antibacterial drugs is evident, and the arsenal against infectious diseases needs to be …

Streptococcus mutans is often cited as the main bacterial pathogen in dental caries,
particularly in early-childhood caries (ECC). S. mutans may not act alone; Candida albicans …

This review aims to analyze propolis as a potential raw material for the development and
manufacture of new health-promoting products. Many scientific publications were retrieved …

The importance of Streptococcus mutans in the etiology and pathogenesis of dental caries is
certainly controversial, in part because excessive attention is paid to the numbers of S …

In the history of human medicine, antibiotics represent epochal examples of medical
progress. However, with an approaching antibiotic crisis due to the emergence and …

Pathogenic oral biofilms are universal, chronic, and costly. Despite advances in
understanding the mechanisms of biofilm formation and persistence, novel and effective …