The effects of childhood maltreatment on brain structure, function and connectivity
MH Teicher, JA Samson, CM Anderson… - Nature reviews …, 2016 - nature.com
Maltreatment-related childhood adversity is the leading preventable risk factor for mental
illness and substance abuse. Although the association between maltreatment and …
illness and substance abuse. Although the association between maltreatment and …
Brain circuit dysfunction in post-traumatic stress disorder: from mouse to man
Post-traumatic stress disorder (PTSD) is a prevalent, debilitating and sometimes deadly
consequence of exposure to severe psychological trauma. Although effective treatments …
consequence of exposure to severe psychological trauma. Although effective treatments …
Post-traumatic stress disorder
Post-traumatic stress disorder (PTSD) occurs in 5–10% of the population and is twice as
common in women as in men. Although trauma exposure is the precipitating event for PTSD …
common in women as in men. Although trauma exposure is the precipitating event for PTSD …
[HTML][HTML] Epigenetic modifications in stress response genes associated with childhood trauma
Adverse childhood experiences (ACEs) may be referred to by other terms (eg, early life
adversity or stress and childhood trauma) and have a lifelong impact on mental and physical …
adversity or stress and childhood trauma) and have a lifelong impact on mental and physical …
[HTML][HTML] The role of the medial prefrontal cortex in the conditioning and extinction of fear
TF Giustino, S Maren - Frontiers in behavioral neuroscience, 2015 - frontiersin.org
Once acquired, a fearful memory can persist for a lifetime. Although learned fear can be
extinguished, extinction memories are fragile. The resilience of fear memories to extinction …
extinguished, extinction memories are fragile. The resilience of fear memories to extinction …
The biological effects of childhood trauma
MD De Bellis, A Zisk - Child and Adolescent Psychiatric …, 2014 - childpsych.theclinics.com
The Biological Effects of Childhood Trauma - Child and Adolescent Psychiatric Clinics Skip to
Main Content Advertisement Child and Adolescent Psychiatric Clinics of North America Log in …
Main Content Advertisement Child and Adolescent Psychiatric Clinics of North America Log in …
[HTML][HTML] Fear and the defense cascade: clinical implications and management
K Kozlowska, P Walker, L McLean… - Harvard review of …, 2015 - journals.lww.com
Evolution has endowed all humans with a continuum of innate, hard-wired, automatically
activated defense behaviors, termed the defense cascade. Arousal is the first step in …
activated defense behaviors, termed the defense cascade. Arousal is the first step in …
Mental disorders as causal systems: A network approach to posttraumatic stress disorder
Debates about posttraumatic stress disorder (PTSD) often turn on whether it is a timeless,
cross-culturally valid natural phenomenon or a socially constructed idiom of distress. Most …
cross-culturally valid natural phenomenon or a socially constructed idiom of distress. Most …
Childhood maltreatment and psychopathology: A case for ecophenotypic variants as clinically and neurobiologically distinct subtypes
MH Teicher, JA Samson - American journal of psychiatry, 2013 - Am Psychiatric Assoc
Objective Childhood maltreatment increases risk for psychopathology. For some highly
prevalent disorders (major depression, substance abuse, anxiety disorders, and …
prevalent disorders (major depression, substance abuse, anxiety disorders, and …
Biological studies of post-traumatic stress disorder
Post-traumatic stress disorder (PTSD) is the only major mental disorder for which a cause is
considered to be known: that is, an event that involves threat to the physical integrity of …
considered to be known: that is, an event that involves threat to the physical integrity of …