An African perspective on the genetic risk of chronic kidney disease: a systematic review

C George, YY Yako, IG Okpechi, TE Matsha… - BMC medical …, 2018 - Springer
Abstract Background Individuals of African ethnicity are disproportionately burdened with
chronic kidney disease (CKD). However, despite the genetic link, genetic association …

[HTML][HTML] Epinephrine

R Dalal, D Grujic - StatPearls [Internet], 2023 - ncbi.nlm.nih.gov
Objectives: Outline the various indications for epinephrine. Review the mechanism of action
of epinephrine. Identify the potential adverse events associated with epinephrine …

Renalase rs2296545 variant improve hypertension susceptibility by modifying binding affinity to catecholamines in obstructive sleep apnea

H Shen, J Yang, W Xue, Z Wei, L Li, J Guan, X Li… - Hypertension …, 2024 - nature.com
Obstructive sleep apnea (OSA), a condition often linked with hypertension, has an undefined
relationship with renalase, a protein known for regulating blood pressure. This study aimed …

Association of renalase SNPs rs2296545 and rs2576178 with the risk of hypertension: a meta-analysis

YB Lv, Y Wang, WG Ma, DY Yan, WL Zheng, C Chu… - PLoS …, 2016 - journals.plos.org
Background/Aims Two renalase single nucleotide polymorphisms (SNPs) rs2296545 and
rs2576178 have been reported to be associated with the susceptibility to hypertension (HT) …

A protective role of renalase in diabetic nephropathy

J Yin, X Liu, T Zhao, R Liang, R Wu, F Zhang… - Clinical …, 2020 - portlandpress.com
Renalase, a recently discovered secreted flavoprotein, exerts anti-apoptotic and anti-
inflammatory effects against renal injury in acute and chronic animal models. However …

Renalase gene Glu37Asp polymorphism affects susceptibility to diabetic retinopathy in type 2 diabetes mellitus

M Buraczynska, K Gwiazda-Tyndel, B Drop… - Acta Diabetologica, 2021 - Springer
Aims Renalase (RNLS) is an enzyme with monoamine oxidase activity that metabolizes
circulating catecholamines. The RNLS gene Asp37Glu missense polymorphism …

Renalase gene polymorphisms and plasma levels are associated with preeclampsia: a hospital-based study in the Chinese cohort

X Li, Q Huang, J Xu - Women & Health, 2021 - Taylor & Francis
Preeclampsia (PE) is one of the major contributors to maternal and fetal mortality worldwide.
Many host-related biomolecules regulate the pathophysiology of PE. The current study aims …

BRASH syndrome: a case report

VK Vishnu, N Jamshed, VT Amrithanand… - The Journal of …, 2021 - Elsevier
Background BRASH syndrome, a relatively new entity, has been described in the recent
literature. It is defined as a combination of bradycardia, renal failure, atrioventricular nodal …

The early diagnostic value of serum renalase level in diabetic kidney disease and diabetic macroangiopathy: a retrospective case–control study

L Jin, W Wang, R Zhang, J Shen… - … Advances in Chronic …, 2024 - journals.sagepub.com
Background: Diabetic kidney disease (DKD) is a severe complication of diabetes mellitus
and is associated with an increased risk of end-stage renal disease (ESRD) and …

Rs10887800 renalase gene polymorphism influences the level of circulating renalase in patients undergoing hemodialysis but not in healthy controls

A Stec - BMC nephrology, 2017 - Springer
Background Human renalase (RNLS), a recently identified flavoprotein with oxidoreductase
activity, is secreted into blood by kidneys and metabolizes circulating catecholamines …