Biomedical applications of microfluidic devices: a review

G Gharib, İ Bütün, Z Muganlı, G Kozalak, İ Namlı… - Biosensors, 2022 - mdpi.com
Both passive and active microfluidic chips are used in many biomedical and chemical
applications to support fluid mixing, particle manipulations, and signal detection. Passive …

Microfluidic systems for hydrodynamic trapping of cells and clusters

Q Luan, C Macaraniag, J Zhou, I Papautsky - Biomicrofluidics, 2020 - pubs.aip.org
Microfluidic devices have been widely applied to trapping and isolation of cells and clusters
for controllable intercellular environments and high-throughput analysis, triggering …

Overcoming diffusion-limited trapping in nanoaperture tweezers using opto-thermal-induced flow

A Kotnala, PS Kollipara, J Li, Y Zheng - Nano letters, 2019 - ACS Publications
Nanoaperture-based plasmonic tweezers have shown tremendous potential in trapping,
sensing, and spectroscopic analysis of nano-objects with single-molecule sensitivity …

Active microparticle manipulation: Recent advances

K Cheng, J Guo, Y Fu, J Guo - Sensors and Actuators A: Physical, 2021 - Elsevier
Microparticle manipulation is mainly needed in several applications like bioanalysis,
disease diagnosis, self-cleaning surfaces, as well as drug delivery. The movement of …

Single-cell metabolite analysis on a microfluidic chip

C Wang, W Hu, L Guan, X Yang, Q Liang - Chinese Chemical Letters, 2022 - Elsevier
Metabolites can directly reflect and modulate cell responses and phenotypical changes by
influencing energy balances, intercellular signals, and many other cellular functions …

Nanomaterials meet microfluidics: improved analytical methods and high-throughput synthetic approaches

T Chen, S Yin, J Wu - TrAC Trends in Analytical Chemistry, 2021 - Elsevier
In recent years, both nanomaterials (NMs) and microfluidics have unprecedented
development. NMs with specific morphologies and versatile surface functionalization offer …

Approaches for manufacture, formulation, targeted delivery and controlled release of phage-based therapeutics

DJ Malik - Current Opinion in Biotechnology, 2021 - Elsevier
A future successful bacteriophage industry requires development of robust scalable
manufacturing platforms for upstream production of high phage titres and their downstream …

Automated electrokinetic stretcher for manipulating nanomaterials

BW Soh, ZE Ooi, E Vissol-Gaudin, CJ Leong… - Lab on a Chip, 2023 - pubs.rsc.org
In this work, we present an automated platform for trapping and stretching individual micro-
and nanoscale objects in solution using electrokinetic forces. The platform can trap objects …

Opto-hydrodynamic tweezers

S Vasantham, A Kotnala, Y Promovych, P Garstecki… - Lab on a Chip, 2024 - pubs.rsc.org
Optical fiber tweezers offer a simple, low-cost and portable solution for non-invasive trapping
and manipulation of particles. However, single-fiber tweezers require fiber tip modification …

Artificial Intelligence Assisted Pharmaceutical Crystallization

Z Zhu, Y Zhang, Z Wang, W Tang, J Wang… - Crystal Growth & …, 2024 - ACS Publications
The ever-increasing demand for novel drug development has spurred the adaptation of
conventional research methods in the era of artificial intelligence. Pharmaceutical …