Cannabinoids in the landscape of cancer

N Mangal, S Erridge, N Habib, A Sadanandam… - Journal of cancer …, 2021 - Springer
Introduction Cannabinoids are a group of terpenophenolic compounds derived from the
Cannabis sativa L. plant. There is a growing body of evidence from cell culture and animal …

The endocannabinoid system: A target for cancer treatment

C Laezza, C Pagano, G Navarra, O Pastorino… - International journal of …, 2020 - mdpi.com
In recent years, the endocannabinoid system has received great interest as a potential
therapeutic target in numerous pathological conditions. Cannabinoids have shown an …

Modulation of the endocannabinoid system as a potential anticancer strategy

R Ramer, R Schwarz, B Hinz - Frontiers in pharmacology, 2019 - frontiersin.org
Currently, the involvement of the endocannabinoid system in cancer development and
possible options for a cancer-regressive effect of cannabinoids are controversially …

Therapeutic applications of cannabinoids

N Maurya, BK Velmurugan - Chemico-biological interactions, 2018 - Elsevier
The psychoactive property of cannabinoids is well known and there has been a continuous
controversy regarding the usage of these compounds for therapeutic purposes all over the …

Insights into the effects of the endocannabinoid system in cancer: a review

AI Fraguas‐Sánchez, C Martín‐Sabroso… - British journal of …, 2018 - Wiley Online Library
In the last few decades, the endocannabinoid system has attracted a great deal of interest in
terms of its applications to clinical medicine. In particular, its applications in cancer probably …

Cannabinoids as anticancer drugs

R Ramer, B Hinz - Advances in Pharmacology, 2017 - Elsevier
The endocannabinoid system encompassing cannabinoid receptors, endogenous receptor
ligands (endocannabinoids), as well as enzymes conferring the synthesis and degradation …

Pharmacological and toxicological effects of phytocannabinoids and recreational synthetic cannabinoids: Increasing risk of public health

VN Bukke, M Archana, R Villani, G Serviddio… - Pharmaceuticals, 2021 - mdpi.com
Synthetic Cannabinoids (CBs) are a novel class of psychoactive substances that have
rapidly evolved around the world with the addition of diverse structural modifications to …

[HTML][HTML] Cannabinoid-mediated targeting of mitochondria on the modulation of mitochondrial function and dynamics

RF Malheiro, H Carmo, F Carvalho, JP Silva - Pharmacological Research, 2023 - Elsevier
Mitochondria play a critical role in the regulation of several biological processes (eg,
programmed cell death, inflammation, neurotransmission, cell differentiation). In recent …

The interplay between cancer biology and the endocannabinoid system—Significance for cancer risk, prognosis and response to treatment

E Moreno, M Cavic, A Krivokuca, EI Canela - Cancers, 2020 - mdpi.com
Simple Summary This review analyses the complex involvement of the various components
of the endocannabinoid system (ECS) in the susceptibility to cancer, prognosis, and …

Antimicrobial and cytotoxic effects of cannabinoids: an updated review with future perspectives and current challenges

MA Saleemi, N Yahaya, NNM Zain, M Raoov, YK Yong… - Pharmaceuticals, 2022 - mdpi.com
The development of new antibiotics is urgently needed to combat the threat of bacterial
resistance. New classes of compounds that have novel properties are urgently needed for …