Long non-coding RNAs as the critical regulators of doxorubicin resistance in tumor cells

G Khalili-Tanha, M Moghbeli - Cellular & Molecular Biology Letters, 2021 - Springer
Resistance against conventional chemotherapeutic agents is one of the main reasons for
tumor relapse and poor clinical outcomes in cancer patients. Various mechanisms are …

Sensitization of tumor cells to chemotherapy by natural products: A systematic review of preclinical data and molecular mechanisms

RG de Oliveira Júnior, AFC Adrielly… - Fitoterapia, 2018 - Elsevier
Purpose Tumor cells are spontaneously or adaptively resistant to chemotherapeutic drugs,
eventually leading to the selection of multiresistant cells responsible for tumor growth and …

Cytotoxicity of eupatorin in MCF-7 and MDA-MB-231 human breast cancer cells via cell cycle arrest, anti-angiogenesis and induction of apoptosis

NA Razak, N Abu, WY Ho, NR Zamberi, SW Tan… - Scientific reports, 2019 - nature.com
Eupatorin has been reported with in vitro cytotoxic effect on several human cancer cells.
However, reports on the mode of action and detail mechanism of eupatorin in vitro in breast …

2-Benzhydrylsulfinyl-N-hydroxyacetamide-Na extracted from fig as a novel cytotoxic and apoptosis inducer in SKOV-3 and AMJ-13 cell lines via P53 and caspase-8 …

HNK Al-Salman, ET Ali, M Jabir, GM Sulaiman… - European food research …, 2020 - Springer
In this study, the fruits of both mature and air-dried figs were exposed to selective sequential
extracting processes using soxhlet. Different polarity and non-polarity solvents were used to …

Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways

YJ Huang, CK Yang, PL Wei, TT Huynh… - Journal of hematology & …, 2017 - Springer
Background An increased expression of Yes-associated protein (YAP1) has been shown to
promote tumorigenesis in many cancer types including colon. However, the role of YAP1 in …

The long noncoding RNA D63785 regulates chemotherapy sensitivity in human gastric cancer by targeting miR-422a

Z Zhou, Z Lin, Y He, X Pang, Y Wang… - … Therapy-Nucleic Acids, 2018 - cell.com
Gastric cancer is one of the most prevalent tumor types in the world. Chemotherapy is the
most common choice for cancer treatment. However, chemotherapy resistance and adverse …

Normal breast epithelial MCF-10A cells to evaluate the safety of carbon dots

N Vale, S Silva, D Duarte, DMA Crista… - RSC Medicinal …, 2021 - pubs.rsc.org
The human normal breast cell line MCF-10A is being widely used as a model in toxicity
studies due to its structural similarity to the normal human mammary epithelium. Over the …

A smart bioresponsive nanosystem with dual-modal imaging for drug visual loading and targeted delivery

J Peng, P Gong, S Li, F Kong, X Ge, B Wang… - Chemical Engineering …, 2020 - Elsevier
Most of present studies are focusing on improving cancer therapy effect by synthesizing new
carriers or drugs, while little attention is paid to develop new drug loading patterns and …

Identification of cancer hub gene signatures associated with immune-suppressive tumor microenvironment and ovatodiolide as a potential cancer immunotherapeutic …

JH Chen, ATH Wu, B Lawal, DTW Tzeng, JC Lee… - Cancers, 2021 - mdpi.com
Simple Summary In order to identify common genes associated with the pathology of
multiple cancers, we integrated differential expressed gene (DEGs) from datasets of six …

Anisomeles indica Extracts and Their Constituents Suppress the Protein Expression of ACE2 and TMPRSS2 In Vivo and In Vitro

YR Chen, WP Jiang, JS Deng, YN Chou… - International Journal of …, 2023 - mdpi.com
Coronavirus disease 2019 (COVID-19), stemming from severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has had a profound global impact. This highly contagious …