The family of VPS10p-Domain (D) receptors comprises five members named SorLA, Sortilin,
SorCS1, SorCS2 and SorCS3. While their physiological roles remain incompletely resolved …

Huntington's disease (HD) is a fatal and pure genetic disease with a progressive loss of
medium spiny neurons (MSN). HD is caused by expanded polyglutamine repeats in the …

Huntington's disease (HD) is a neurodegenerative disorder caused by a mutation in the
huntingtin (HTT) gene, leading to a toxic version of the HTT protein. There are currently no …

Huntington's Disease (HD) is a severely debilitating neurodegenerative disorder in which
sufferers exhibit different combinations of movement disorders, dementia, and behavioral or …

In current aging societies, diabetes mellitus and neurodegenerative diseases represented
by Alzheimer's disease are highly prevalent among adults, especially the elderly all over the …

Huntington's disease (HD) is a progressively debilitating neurodegenerative disease
exhibiting autosomal-dominant inheritance. It is caused by an unstable expansion in the …

Huntington's disease (HD) is a progressive inherited neurodegenerative disease caused by
a CAG repeat expansion in the huntingtin gene, which is translated into the pathologic …

Single-cell transcriptomics is essential for understanding biological variability among cells in
a heterogenous population. Acquiring high-quality single-cell sequencing data from a tissue …

Background: Increasing evidence links impaired brain insulin signaling and insulin
resistance to the development of Alzheimer's disease (AD). Objective: This evidence …

Huntington's disease (HD) is a progressive inherited neurodegenerative disease caused by
a CAG repeat expansion in the huntingtin gene, which is translated into the pathologic …