Current and future biomarkers in multiple sclerosis

J Yang, M Hamade, Q Wu, Q Wang, R Axtell… - International journal of …, 2022 - mdpi.com
Multiple sclerosis (MS) is a debilitating autoimmune disorder. Currently, there is a lack of
effective treatment for the progressive form of MS, partly due to insensitive readout for …

Body fluid biomarkers in multiple sclerosis

M Comabella, X Montalban - The Lancet Neurology, 2014 - thelancet.com
Biomarkers can be thought of as multifaceted indicators of healthy status or of pathological
disorders. The study of multiple sclerosis can benefit from the use of biomarkers because of …

The utility of cerebrospinal fluid analysis in patients with multiple sclerosis

M Stangel, S Fredrikson, E Meinl, A Petzold… - Nature Reviews …, 2013 - nature.com
Diagnosis of multiple sclerosis (MS) requires the exclusion of other possible diagnoses. For
this reason, the cerebrospinal fluid (CSF) should be routinely analysed in patients with a first …

Neuronal and glial CSF biomarkers in multiple sclerosis: A systematic review and meta-analysis

S Momtazmanesh, P Shobeiri… - Reviews in the …, 2021 - degruyter.com
Multiple sclerosis (MS) is a neurodegenerative disease associated with inflammatory
demyelination and astroglial activation, with neuronal and axonal damage as the leading …

Combination of CSF N-acetylaspartate and neurofilaments in multiple sclerosis

CE Teunissen, E Iacobaeus, M Khademi, L Brundin… - Neurology, 2009 - AAN Enterprises
Objective: Axonal degeneration is the likely cause of disease progression in multiple
sclerosis (MS). Our previous results indicated that neuron-specific N-acetylaspartate (NAA) …

Serum biomarkers in myelin oligodendrocyte glycoprotein antibody–associated disease

H Kim, EJ Lee, S Kim, LK Choi, K Kim… - Neurology …, 2020 - AAN Enterprises
Objective To test the hypothesis that the pattern of serum biomarkers of disease activity and
disability in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD) will …

Disease biomarkers in multiple sclerosis: potential for use in therapeutic decision making

VK Harris, SA Sadiq - Molecular diagnosis & therapy, 2009 - Springer
Multiple sclerosis (MS) is an autoimmune disorder of the brain and spinal cord that
predominantly affects white matter. MS has a variable clinical presentation and has no …

The role of Tau beyond Alzheimer's disease: a narrative review

E Virgilio, F De Marchi, E Contaldi, U Dianzani… - Biomedicines, 2022 - mdpi.com
Nowadays, there is a need for reliable fluid biomarkers to improve differential diagnosis,
prognosis, and the prediction of treatment response, particularly in the management of …

Clinical, MRI, and CSF markers of disability progression in multiple sclerosis

A Gajofatto, M Calabrese, MD Benedetti… - Disease …, 2013 - Wiley Online Library
Multiple sclerosis (MS) is a chronic disorder of the central nervous system (CNS) in which
the complex interplay between inflammation and neurodegeneration determines varying …

[HTML][HTML] Biochemical biomarkers for multiple sclerosis

J Maroto-García, A Martínez-Escribano… - Clinica Chimica …, 2023 - Elsevier
Introduction Multiple sclerosis (MS) is the most frequent demyelinating disease of the central
nervous system. Although there is currently there is no definite cure for MS, new therapies …