Plant protease inhibitors in therapeutics-focus on cancer therapy

S Srikanth, Z Chen - Frontiers in pharmacology, 2016 - frontiersin.org
Plants are known to have many secondary metabolites and phytochemical compounds
which are highly explored at biochemical and molecular genetics level and exploited …

The role of nutraceutical proteins and peptides in apoptosis, angiogenesis, and metastasis of cancer cells

EG De Mejia, VP Dia - Cancer and Metastasis Reviews, 2010 - Springer
The process of carcinogenesis is complex and not easy to eliminate. It includes the initial
occurrence of genetic alterations which can lead to the inactivation of tumor-suppressor …

Chemopreventive role of food-derived proteins and peptides: A review

B Hernández-Ledesma, CC Hsieh - Critical reviews in food science …, 2017 - Taylor & Francis
Cancer is one of the leading causes of mortality and disability worldwide. Although great
advances in cancer treatments such as chemotherapy, surgery, and radiation are currently …

A protein with antiproliferative, antifungal and HIV-1 reverse transcriptase inhibitory activities from caper (Capparis spinosa) seeds

SK Lam, TB Ng - phytomedicine, 2009 - Elsevier
A protein exhibiting an N-terminal amino acid sequence with some similarity to
imidazoleglycerol phosphate synthase was purified from fresh Capparis spinosa melon …

Thermostable Kunitz trypsin inhibitor with cytokine inducing, antitumor and HIV-1 reverse transcriptase inhibitory activities from Korean large black soybeans

EF Fang, JH Wong, TB Ng - Journal of bioscience and bioengineering, 2010 - Elsevier
A large number of trypsin inhibitors belonging to various types have been purified from
different kinds of legumes. In this study, by using liquid chromatography, a Kunitz type …

Characterization of cDNAs Encoding Two Distinct Miraculin-like Proteins and Stress-related Modulation of the Corresponding mRNAs in Citrus jambhiri Lush

S Tsukuda, K Gomi, H Yamamoto, K Akimitsu - Plant molecular biology, 2006 - Springer
Two distinct full-length cDNAs from rough lemon that encoded miraculin-like proteins were
isolated by random amplification of cDNA ends (RACEs), based on sequence information …

A serine proteinase inhibitor isolated from Tamarindus indica seeds and its effects on the release of human neutrophil elastase

J Fook, LLP Macedo, G Moura, FM Teixeira… - Life sciences, 2005 - Elsevier
Proteinaceous inhibitors with high inhibitory activities against human neutrophil elastase
(HNE) were found in seeds of the Tamarind tree (Tamarindus indica). A serine proteinase …

Insecticidal and Antifungal Activity of a Protein from Pouteria torta Seeds with Lectin-like Properties

APA Boleti, MGM Freire, MB Coelho… - Journal of Agricultural …, 2007 - ACS Publications
This paper describes the purification and characterization of a novel protein from the seeds
of Pouteria torta (family Sapotaceae). The protein was purified by a combination of gel …

[HTML][HTML] Comprehensive review on Caelsalpinioideae lectins: From purification to biological activities

BS Cavada, VR Pinto-Junior, VJS Osterne… - International Journal of …, 2020 - Elsevier
Lectins are a class of proteins with specific and reversible carbohydrate binding properties.
Plant lectins constitute the group of these proteins most studied, placing emphasis on the …

[HTML][HTML] Crystal structure of Crataeva tapia bark protein (CrataBL) and its effect in human prostate cancer cell lines

R da Silva Ferreira, D Zhou, JG Ferreira, MCC Silva… - PLoS …, 2013 - journals.plos.org
A protein isolated from the bark of Crataeva tapia (CrataBL) is both a Kunitz-type plant
protease inhibitor and a lectin. We have determined the amino acid sequence and three …