Application of metabolomics to the discovery of biomarkers for ischemic stroke in the murine model: a comparison with the clinical results

J Jia, H Zhang, X Liang, Y Dai, L Liu, K Tan, R Ma… - Molecular …, 2021 - Springer
Ischemic stroke (IS) is a major cause of mortality and disability worldwide. However, the
pathogenesis of IS remains unknown, and methods for early prediction and diagnosis of IS …

Fluid biomarkers in stroke: From animal models to clinical care

A Dias, L Silva, J Moura, D Gabriel… - Acta Neurologica …, 2022 - Wiley Online Library
Stroke is a leading cause of death and disability worldwide. Stroke prevention, early
diagnosis, and efficient acute treatment are priorities to successfully impact stroke death and …

Acute ischemic stroke triggers a cellular senescence-associated secretory phenotype

C Torres-Querol, P Torres, N Vidal, M Portero-Otin… - Scientific Reports, 2021 - nature.com
Senescent cells are capable of expressing a myriad of inflammatory cytokines and this pro-
inflammatory phenomenon is known as senescence-associated secretory phenotype …

[HTML][HTML] Detection of acute ischemic stroke and backtracking stroke onset time via machine learning analysis of metabolomics

Y Zhang, D Zhu, T Li, X Wang, L Zhao, X Yang… - Biomedicine & …, 2022 - Elsevier
The time window from stroke onset is critical for the treatment decision. However, in
unknown onset stroke, it is often difficult to determine the exact onset time because of the …

Sex as a biological variable in determining the metabolic changes influencing acute ischemic stroke outcomes—Where is the data: A systematic review

L Dylla, HM Higgins, C Piper, SN Poisson… - Frontiers in …, 2022 - frontiersin.org
Women continue to face a greater lifetime morbidity and mortality from stroke and have been
shown to respond differently to stroke treatments compared to men. Since 2016, updated …

Discovery of a new biomarker pattern for differential diagnosis of acute ischemic stroke using targeted metabolomics

R Sun, Y Li, M Cai, Y Cao, X Piao - Frontiers in Neurology, 2019 - frontiersin.org
Stroke is one of the leading causes of disability all over the world. However, biomarkers for
fast differential diagnosis of acute ischemic stroke (AIS) from vertigo or headache, remains …

Plasmalogens and Octanoylcarnitine Serve as Early Warnings for Central Retinal Artery Occlusion

C Wang, Y Li, J Feng, H Liu, Y Wang, Y Wan… - Molecular …, 2024 - Springer
Central retinal artery occlusion (CRAO) is a kind of ophthalmic emergency which may cause
loss of functional visual acuity. However, the limited treatment options emphasize the …

Serum metabolomic profiles reveal the impact of BuZangTongLuo formula on metabolic pathways in diabetic mice with hindlimb ischemia

J Zheng, Y Guo, B Hu, L Zhu, Y Yang, S Li, N Li… - Journal of …, 2020 - Elsevier
Abstract Ethnopharmacological relevance BuZangTongLuo Formula (BZTLF) was the
decoction of eight traditional Chinese medicines including Astragalus membranaceus …

Remote ischemic conditioning modulates inflammatory response and metabolic pathways

C Torres-Querol, R Pamplona, G Arqué, F Purroy - bioRxiv, 2023 - biorxiv.org
Remote ischemic conditioning (RIC) is an endogenous procedure that reduces ischemic
injury by repeated transient mechanical obstruction of vessels at a remote limb. However …

Remote Ischemic Preconditioning and Postconditioning Reduced Cerebral Ischemic Injury Modulating Inflammatory Responses and Metabolic Pathways

C Torres-Querol, R Pamplona, G Arqué… - Available at SSRN … - papers.ssrn.com
Remote ischemic conditioning (RIC) is an endogenous procedure that reduces ischemic
injury by repeated transient mechanical obstruction of vessels at a remote limb from the …