Cell–cell fusion remains the least understood type of membrane fusion process. However,
the last few years have brought about major advances in understanding fusion between …

Cell-cell fusion is essential for fertilization and organ development. Dedicated proteins
known as fusogens are responsible for mediating membrane fusion. However, until recently …

Motivation Understanding the relationship between the sequence, structure, binding energy,
binding kinetics and binding thermodynamics of protein–protein interactions is crucial to …

Distinct morphologies of the mitochondrial network support divergent metabolic and
regulatory processes that determine cell function and fate,–. The mechanochemical GTPase …

Sperm− oocyte membrane fusion is one of the most important events for fertilization. So far,
IZUMO1 and Fertilization Influencing Membrane Protein (FIMP) on the sperm membrane …

Fertilization is defined as the union of two gametes. During fertilization, sperm and egg fuse
to form a diploid zygote to initiate prenatal development. In mammals, fertilization involves …

Fertilization is a multistep process that culminates in the fusion of sperm and egg, thus
marking the beginning of a new organism in sexually reproducing species. Despite its …

Fertilization is a fundamental process in sexual reproduction, creating a new individual
through the combination of male and female gametes,,,. The IZUMO1 sperm membrane …

Sperm–oocyte fusion is a critical event in mammalian fertilization, categorized by three
indispensable proteins. Sperm membrane protein IZUMO1 and its counterpart oocyte …

Fertilization is the fundamental process that initiates the development of a new individual in
all sexually reproducing species. Despite its importance, our understanding of the molecular …