TFOS DEWS II management and therapy report

L Jones, LE Downie, D Korb, JM Benitez-del-Castillo… - The ocular …, 2017 - Elsevier
The members of the Management and Therapy Subcommittee undertook an evidence-
based review of current dry eye therapies and management options. Management options …

Novel drug delivery systems for the management of dry eye

N Nagai, H Otake - Advanced drug delivery reviews, 2022 - Elsevier
Dry eye disease (DED) is a frequently observed eye complaint, which has recently attracted
considerable research interest. Conventional therapy for DED involves the use of artificial …

Artificial tears: biological role of their ingredients in the management of dry eye disease

M Labetoulle, JM Benitez-del-Castillo… - International journal of …, 2022 - mdpi.com
Dry eye disease (DED) is the most common ocular surface disease, characterized by
insufficient production and/or instability of the tear film. Tear substitutes are usually the first …

Dry eye management: targeting the ocular surface microenvironment

X Zhang, V Jeyalatha M, Y Qu, X He, S Ou, J Bu… - International journal of …, 2017 - mdpi.com
Dry eye can damage the ocular surface and result in mild corneal epithelial defect to
blinding corneal pannus formation and squamous metaplasia. Significant progress in the …

Modern approach to the treatment of dry eye, a complex multifactorial disease: a PICASSO board review

P Aragona, G Giannaccare, R Mencucci… - British Journal of …, 2021 - bjo.bmj.com
Dry eye disease (DED) is a growing public health concern affecting quality of life and visual
function, with a significant socio-economic impact. It is characterised by the loss of …

The core mechanism of dry eye disease is inflammation

Y Wei, PA Asbell - Eye & contact lens, 2014 - journals.lww.com
Purpose: The purpose of this article is to review the evidence for the hypothesis that the core
mechanism of dry eye disease (DED) is inflammation, including evidence from recent basic …

Treatment of primary Sjögren syndrome: a systematic review

M Ramos-Casals, AG Tzioufas, JH Stone, A Sisó… - Jama, 2010 - jamanetwork.com
Context A variety of topical and systemic drugs are available to treat primary Sjögren
syndrome, although no evidence-based therapeutic guidelines are currently available …

TFOS Lifestyle: impact of nutrition on the ocular surface

M Markoulli, S Ahmad, J Arcot, R Arita… - The ocular …, 2023 - Elsevier
Nutrients, required by human bodies to perform life-sustaining functions, are obtained from
the diet. They are broadly classified into macronutrients (carbohydrates, lipids, and proteins) …

Topical cyclosporine A therapy for dry eye syndrome

CS De Paiva, SC Pflugfelder, SM Ng… - Cochrane Database of …, 2019 - cochranelibrary.com
Background Topical cyclosporine A (also known as ciclosporin A)(CsA) is an anti‐
inflammatory that has been widely used to treat inflammatory ocular surface diseases. Two …

Dysfunctional tear syndrome: dry eye disease and associated tear film disorders–new strategies for diagnosis and treatment

MS Milner, KA Beckman, JI Luchs… - Current opinion in …, 2017 - journals.lww.com
Dysfunctional tear syndrome (DTS) is a common and complex condition affecting the ocular
surface. The health and normal functioning of the ocular surface is dependent on a stable …